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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Telocytes might help with skin repair and regeneration.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male pattern baldness involves genetics, hormones, and needs better treatments.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Cathepsin L is essential for normal hair growth and development.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Electrolysis is effective for permanent hair removal, but technique is key to avoid scarring, and sometimes hormonal treatment is needed for women with hirsutism.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.