13 citations
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April 1964 in “PubMed” This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.
2 citations
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July 2009 in “Mayo Clinic Proceedings” This case report describes a 66-year-old woman diagnosed with porphyria cutanea tarda, characterized by painless vesicular lesions on sun-exposed areas and associated with hemochromatosis, and managed effectively with phlebotomy.
1 citations
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January 2017 in “Pharmaceutica Analytica Acta” This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
December 2023 in “Natural product research” This study found that compound 4 from Urtica triangularis subsp. pinnatifida exhibited stronger anti-BPH activity against BPH-1 cells with an IC50 of 79.75 μM compared to finasteride's IC50 of 91.8 μM, while compounds 1, 2, and 5 showed moderate activity.
November 2023 in “Plants” This study evaluated compounds from Jatropha cordata bark, finding that a sterol mixture and n-heptyl ferulate demonstrated notable anti-inflammatory activity in murine macrophage cells without toxicity, suggesting potential for treating chronic inflammation.
June 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” GLABRA2 represses root hair formation by inhibiting a specific gene.
9 citations
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January 1966 in “Economic botany” Plant-based ingredients in hair care are being replaced by synthetic alternatives.
8 citations
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October 2002 in “Journal Of Clinical Periodontology” This study suggests that levamisole and finasteride can significantly reduce DHT levels in human gingival fibroblasts, potentially addressing phenytoin-induced gingival overgrowth.
39 citations
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May 2006 in “Molecular Plant-Microbe Interactions” This study suggests that fusaric acid at nontoxic concentrations may activate signal transduction in plants which could aid in the plant-defense responses against Fusarium spp.
4 citations
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February 2021 in “Plant journal” This study found that the protein OsUEV1B is essential for maintaining phosphate balance in rice, with Pi deficiency leading to its inhibition and causing overaccumulation of phosphate in mutants.
12 citations
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December 2022 in “Annals of Phytomedicine An International Journal” This review discusses the historical and potential medical uses of Cyperus rotundus rhizomes, but reports no new clinical results and emphasizes the need for further study on its pharmacognostic properties.
May 2024 in “EAS Journal of Pharmacy and Pharmacology” In this study, researchers used molecular docking to show that compounds from pomegranate peels, such as apigenin, luteolin, and taxifolin, effectively inhibit the enzyme 5α-reductase, suggesting potential anti-alopecic properties.
37 citations
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September 2008 in “Plant Signaling & Behavior” In this study, overexpression of the gene OsPHR2 in rice led to increased root growth and phosphate accumulation in shoots, suggesting its role in phosphate signaling and homeostasis.
June 2009 in “Mayo Clinic Proceedings” This report describes a 66-year-old woman's diagnosis of porphyria cutanea tarda, suggested by her painless blisters on sun-exposed areas, pink urine, and elevated urinary porphyrins.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit and other natural ingredients, reporting that the dye provided satisfactory color, stability, scalp pH compatibility, and did not cause irritation, also demonstrating antioxidant and antimicrobial properties that benefit scalp health.
January 2026 in “Cosmetics” In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.
2 citations
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May 2023 in “Life” This review summarizes the mechanisms by which Plumbagin, a naphthoquinone derived from plants, may impact inflammation and explores its potential biological effects, highlighting areas that require further comprehensive research before considering it for therapeutic use.
17 citations
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January 2012 in “IOSR Journal of Environmental Science Toxicology and Food Technology” This study found that high doses of ethyl acetate extract from Tridax procumbens can have specific toxic effects in rats, including organ damage and significant changes in some serum biochemical parameters.
April 2018 in “The Journal of Urology” This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
28 citations
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December 2018 in “Plant, cell & environment/Plant, cell and environment” This study found that the PLC2 gene plays a critical role in auxin-mediated root development in Arabidopsis, influencing root growth and PIN2 distribution.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
7 citations
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September 2024 in “PLANT PHYSIOLOGY” This study in Arabidopsis thaliana found that exposure to volatile compounds from Penicillium aurantiogriseum promotes root hair growth through signaling involving RALF22, ethylene, auxin, and photosynthesis, and that RALF22 plays a crucial role in the plants' response to these compounds.
1 citations
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January 2022 in “Food & Function” This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.
This study provides detailed taxonomic and pharmacognostic analyses to authenticate and standardize seven herbal medicines, aiding in their differentiation from common adulterants for improved identification and classification.
In this study, a 75% ethanol extract of Fructus Psoraleae was found to significantly inhibit 5-α reductase and promote hair growth in mice, indicating its potential as a treatment for androgenetic alopecia through modulation of the Nrf2-Keap1 pathway.
110 citations
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September 2017 in “Molecules” This review discusses the phytochemistry, pharmacology, pharmacokinetics, and standardization of Forsythiae Fructus, detailing both unripe and ripe forms, but reports no new clinical results.
January 2025 in “European Journal of Pharmacology” This study found that forsythoside A, a compound from Forsythia suspensa, may counteract DHT-induced hair regrowth inhibition by selectively inhibiting TRPV3 channels.
3 citations
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June 2020 in “Pharmacognosy Journal” In this study, researchers developed ethosomes containing Phyllanthus emblica extract and found them to have beneficial properties, including high entrapment efficiency and antioxidant activity, suggesting potential as an alternative product for preventing hair loss.
January 2015 in “International Journal of Pharma and Bio Sciences” This review discusses the traditional medicinal uses of Tridax procumbens, attributing its therapeutic properties to various active phytochemicals, but reports no new clinical findings.
November 2023 in “Turkish journal of botany” In this review, researchers documented 439 plant taxa from 89 families in Türkiye used for ethnomedical treatments of skin diseases or as cosmetics, identifying Plantago lanceolata and several other common species, providing a resource for future studies on herbal remedies for dermatological disorders.