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Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Androgens can both increase and decrease hair growth in different parts of the body.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

Dermoscopy helps diagnose and manage alopecia areata by showing specific hair changes.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Targeted cancer therapies often cause serious skin problems that need careful management.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Bioprinting could improve wound healing but needs more development to match real skin.

Estrogen therapy can reduce skin aging but has cancer risks.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.