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PCOS is caused by both genetics and environmental factors like diet and obesity.

The Rotterdam Study aims to understand various diseases in older adults.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

PGD2 stops hair growth and is higher in bald men with AGA.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Stem cell self-renewal is complex and needs more research for full understanding.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Fat cells in the skin help start healing and form important repair cells after injury.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Scientists created stem cells that can grow hair and skin.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Skin fat helps with body temperature control and has other active roles in health.