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Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Finasteride increases hair count and improves hair growth with low risk of side effects.

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.

Finasteride improves hair growth in men with androgenetic alopecia.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Liposomes could improve how skin care products work but are costly and not very stable.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.