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research Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice
Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
research High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses
Reliable method detects finasteride in human plasma at low doses.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research Gefitinib: An Adverse Effects Profile
Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
research Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study
Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
research High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching
New method detects finasteride in plasma quickly and accurately without clean-up.
research A Phase I Study of Topical Tempol for the Prevention of Alopecia Induced by Whole Brain Radiotherapy
Tempol is safe and may prevent hair loss from brain radiotherapy.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.
research In Vitro Biotransformation of Finasteride in Rat Hepatic Microsomes: Isolation and Characterization of Metabolites
research ST008 Male Androgenetic Alopecia: A New Treatment Paradigm
New treatment improves male hair loss.
research Tolerance and Safety Profile of Sublingual Minoxidil in the Treatment of Androgenic Alopecia
Sublingual minoxidil is a safe and effective treatment for hair loss, especially in women.
research Topical Cetirizine 1% for Treatment of Androgenetic Alopecia
Topical cetirizine 1% increases hair density and may be a promising treatment for hair loss.
research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.
research Drug Repurposing in Dermatology: Molecular Biology and Omics Approach
Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.
research Topical SCD-153, A 4-Methyl Itaconate Prodrug, For The Treatment Of Alopecia Areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
research New Spectrophotometric Methods for the Determination of Minoxidil
New, simple, and cost-effective methods can accurately measure Minoxidil in medicines.
research Direct Hair Growth Promoting Effects of Mycophenolic Acid
Mycophenolic acid may help hair grow by activating pathways important for hair growth.
research Evaluation of Hair Follicles as a Surrogate Tissue for Pharmacodynamic Response in Xenograft Tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
research Minoxidil Topical Foam: A New Kid on the Block
Minoxidil topical foam is a better, less irritating treatment for hair loss.
research Rapid Determination of Minoxidil in Human Plasma Using Ion-Pair HPLC
Quick method to measure minoxidil in blood, accurate and useful for labs.
research Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C
Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.
research Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
research Design of Nanocrystalline Suspension of Dutasteride for Intramuscular Prolonged Delivery
The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.
research Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development
Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
research Pharmaceutical Care in Transplantation: Current Challenges and Future Opportunities
Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.
research Cutaneous Drug Reactions
Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research RP-HPLC Method for Simultaneous Estimation of Finasteride and Tamsulosin in Tablet Formulations
research Long-Acting Microneedle Formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.