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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.

Fluridil safely promotes hair growth in men with androgenetic alopecia.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Niosomes improve minoxidil skin delivery for hair loss treatment.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

The Rotterdam Study aims to understand various diseases in older adults.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Finasteride effectively treats baldness but may cause sexual side effects.

Testosterone's muscle-building effects do not require its conversion to DHT.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

One minoxidil-sensitive potassium channel exists in human hair follicles.