1 citations
,
September 2024 in “Journal of the American Academy of Dermatology” Physician responses are better than ChatGPT for dermatology questions.
51 citations
,
September 2000 in “Acta dermato-venereologica” This study found that PPAR alpha, -delta, and -gamma are expressed in human hair follicle cells, and clofibrate exhibited a beneficial effect on hair follicle survival in culture within a specific concentration range.
5 citations
,
January 2013 in “Otorhinolaryngology clinics : an international journal” This review discusses the use of platelet-rich plasma in cosmetic surgery, highlighting its expanding applications and promising potential in aesthetic treatments, but reports no new empirical findings.
52 citations
,
May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that overexpression of parathyroid hormone-related protein in mice resulted in 30–40% shorter hair due to premature transition into the catagen phase of the hair cycle.
November 2023 in “Scientific Papers Journal VETERINARY SERIES” This review highlights the potential of platelet-rich plasma as a therapeutic tool in animals, noting its mixed efficacy and promising applications in areas like reproduction, but reports no new clinical results.
February 2026 in “The Journal of Sexual Medicine” In this case report, goserelin, a GnRH agonist, was effective in managing stuttering priapism and improving erectile function in a patient with sickle cell disease, suggesting potential for last-line treatment.
138 citations
,
November 2015 in “Journal of Pharmacology and Experimental Therapeutics” This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
July 2026 in “Stem Cell Research & Therapy” This commentary suggests that shifting from inconsistent autologous PRP to more standardized PRP-inspired formulations could improve treatment consistency for alopecia, emphasizing the need for careful characterization and clinical studies to validate safety and efficacy.
December 2012 in “http://isrctn.org/>”
January 2024 in “Journal of Education, Health and Sport” This review discusses the modern production methods, mechanisms of action, and various uses of platelet-rich plasma in medicine, highlighting promising applications but noting the need for more high-quality research.
PRP works well with other treatments for better skin, hair, and scar results.
April 2023 in “Journal of Investigative Dermatology” This study found that sebaceous glands can regenerate after PPARg deletion in adult skin, relying on the hair cycle and FGFR signaling.
April 2026 in “International Journal of Drug Delivery Technology” This review concluded that while topical prostaglandin analogues show some potential in treating androgenetic alopecia, evidence is still limited and no products have regulatory approval.
In this study, researchers found that autologous PRP injections, when used as an adjuvant treatment with topical minoxidil, did not provide a significant increase in hair density compared to placebo in men with androgenetic alopecia in northeastern India.
2 citations
,
June 2015 in “Vestnik dermatologii i venerologii” PRP shows promise for treating certain types of hair loss.
11 citations
,
January 2008 in “International journal of environment and health” This review discusses the environmental contamination and health risks of Platinum Group Elements, highlighting their potential bioaccumulation and associated health issues, especially in vulnerable populations like children, and reports no new experimental findings.
1 citations
,
August 2011 in “Planta Medica” This study reported that bimatoprost significantly increased hair growth in rat vibrissa follicles by enhancing dermal papilla cell proliferation and upregulating cell cycle proteins like CDK2, Cyclin E, and β-catenin.
March 2024 in “Plant physiology” This study found that the transcription factor GLABRA 2 inhibits ethylene production, regulating root hair growth in Arabidopsis under nutrient deficiency conditions.
This study found that the Padina arborescens extract and its component MOGG may prevent hair loss by inhibiting 5α-reductase activity, promoting cell proliferation, opening the KATP channel, and increasing PGE2 production in laboratory settings.
58 citations
,
January 2015 in “International Journal of Trichology” This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.
April 2024 in “Journal of cosmetic dermatology” This article discusses the development of liquid platelet-rich fibrin as a potential improvement over platelet-rich plasma for treating androgenetic alopecia and reports no new clinical results.
1 citations
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December 2019 in “Protetyka Stomatologiczna” This review discusses the use of platelet-rich fibrin in medical fields, especially dentistry, and reports no new clinical results.
November 2025 in “Transfusion Medicine and Hemotherapy” This study found that platelet-rich plasma therapy significantly promoted hair growth in androgenetic alopecia model mice by enhancing autophagy, with effects similar to rapamycin treatment.
22 citations
,
October 2019 in “International Journal of Nanomedicine” This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.
5 citations
,
November 2013 in “Journal of Investigative Dermatology” This study found that mice lacking the glucocorticoid receptor in their epidermis showed increased susceptibility to chemical-induced skin cancer, highlighting the receptor's role in skin carcinogenesis.
10 citations
,
January 2012 in “International Journal of Trichology” PRP helps hair growth in common hair loss disorder.
The study found that the combined administration of regulatory T cells and rapamycin improved outcomes in an experimental model of chronic graft-versus-host disease.
1 citations
,
November 2024 in “Revista Foco” This review suggests that PRP is an effective and safe technique for skin rejuvenation in aesthetic procedures, based on existing literature.
May 2023 in “International Journal of Trichology” In this study, PRP therapy did not show significant effectiveness in treating androgenetic alopecia in patients over a 6-month period, with 45% of participants reporting no improvement in hair growth, although adverse effects were minimal and non-serious.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this case report, a 28-year-old male with androgenetic alopecia experienced significant improvement in hair density and shaft thickness after a three-month platelet-rich plasma therapy regimen, supporting existing literature on PRP's efficacy for early-to-moderate hair loss.