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This chapter reviews various chemical synthesis methods for pharmaceutical compounds and reports no new experimental results.

This study found that loss of epidermal PPARγ in mice altered the expression of many genes related to skin inflammation, keratinization, and sebaceous gland function, indicating its key role in maintaining skin homeostasis.

ChatGPT can be a helpful dermatology resource but should not replace professional consultations.

This study found that DPG promoted wound healing in rat skin, with increased collagen I density, particularly evident within the first 14 days after injury.

This article discusses the use of PRP and long-acting PRP for treating Female Pattern Hair Loss, emphasizing their potential benefits, but reports no new clinical results.

This review summarizes available evidence on the dermatological use of platelet-rich plasma, particularly noting its efficacy for androgenetic alopecia and skin rejuvenation, but highlights significant gaps due to limited high-quality studies.

This study found that intrauterine PRP infusion is a safe and effective treatment for patients with refractory thin endometrium and implantation failures, with the improvement primarily driven by the angiogenic cytokines in PRP.

The authors concluded that their new grading system can effectively classify early female pattern hair loss and evaluate treatment progress.

This study observed that autologous PRP and PDRN injections improved hair thickness and density in women with pattern hair loss, with combined therapy showing greater improvement in thickness than PDRN alone.

This article discusses androgenetic alopecia, emphasizing its prevalence across age groups and noting that it is the most common cause of hair loss in adolescents, but provides no new clinical results.

This study suggests that the progesterone metabolite allopregnanolone and progesterone regulate distinct gene sets involved in glioblastoma cell proliferation, with some overlapping effects modified by finasteride.

This review found potential benefits of PRP for androgenic alopecia but highlighted the need for more rigorous studies to confirm its effectiveness.

This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.

This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.

In this study, patients with generalized pustular psoriasis were classified into subgroups to better understand the disease's variability and assist in treatment selection, highlighting the role of localized infections in triggering flares.

This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.

This review assessed the role of scalp hair Survivin protein in individuals with premature graying, exploring its potential involvement in graying-related processes and highlighting its overexpression in autoimmune diseases that may influence the survival of specific immune cell clones.

This article discusses the factors driving the platelet-rich plasma market in dermatology and reports no clinical results; it highlights the need for more affordable and accessible treatments.

This study found that 15-dPGJ2 promotes apoptosis in human follicular keratinocytes, suggesting its potential role in developing hair loss prevention treatments through DP2 antagonism.

This study utilized a sequence-structure alignment approach to improve the characterization of Class A Rhodopsin GPCR superfamily, including orphan and unclassified receptors, through evolutionary analysis.

This study found that platelet-rich plasma therapy may improve hair density and thickness in androgenetic alopecia, especially in early to moderate stages, though standardization of preparation is needed for consistent results.

This study found that combining CGF with IPL treatment significantly improved skin conditions and quality of life for patients with facial sensitive skin compared to IPL alone, with enhanced wrinkle reduction, skin barrier function, and decreased adverse reactions reported.

This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.

This review discusses the use of platelet-rich plasma in urology and emphasizes the need for further multicenter studies to explore its potential benefits.

This bibliometric analysis reported that PRP is most frequently studied for hair restoration, especially in placebo-controlled trials, although differences in PRP preparation and outcome measures challenge result consistency across studies.

This review discusses the potential therapeutic applications of platelet-rich plasma across several medical fields and reports a lack of standardized protocols and controlled trials to confirm its effectiveness.

This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.

This review discusses the progress and challenges of targeted protein degradation therapies, highlighting the increasing number of degraders in cancer clinical trials and the limited diversity in targeted proteins, primarily focusing on those employing CRL4^CRBN as the E3 ligase.

This study found that mouse embryonic fibroblasts better supported the growth and maintenance of LGR5+ epidermal stem cells compared to porcine fetal fibroblasts, under various culture conditions.

This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.