research Birt-Hogg-Dubé Syndrome: From Gene Discovery to Molecularly Targeted Therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
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60-81 / 81 resultsresearch Lipid Signaling in Keratinocytes: Lipin-1 Plays a Part
Lipin-1 is important for skin cell differentiation and skin barrier function.
research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
research Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes
Interleukin-1 increases keratin K6 production in skin cells.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands
Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in Alzheimer's Disease and Rosacea
Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
research Retinoic Acid Exerts Sexually Dimorphic Effects on Muscle Energy Metabolism and Function
Retinoic acid affects male and female muscle energy use and function differently.
research Targeting the Undifferentiated State of Cancer
Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Does an Apple a Day Keep Away Diseases? Evidence and Mechanism of Action
Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.
research Advances in Platelet Rich Plasma-Derived Extracellular Vesicles for Regenerative Medicine: A Systematic-Narrative Review
Platelet Rich Plasma-Derived Extracellular Vesicles show promise for healing and regeneration but need standardized methods for consistent results.
research Potential Role of Cinnamon (Cinnamomum Verum) to Reduce the Risk of Polycystic Ovary Syndrome by Managing Obesity: A Review
Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).
research The Multiple Consequences Of Obesity
Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
research Comparative Proteomic Analysis of Male and Female Androgenetic Alopecia: Elucidating Gender-Specific Molecular Patterns
Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.
research The Vitamin B5/Coenzyme A Axis: A Target for Immunomodulation?
Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
research Piperine Reduces Hair Oiliness by Inhibiting Adipogenesis of Hair Stem Cells
Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
research An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing the Big Eight Strikes
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
research N,N-Dimethylglycine Sodium Salt Exerts Anti-Inflammatory Effects in Dermatitis Models and Activates Human Epidermal Keratinocytes
N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.