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Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.

Apremilast shows promise for several skin conditions but needs more research.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.

Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Eating healthy, exercising, and changing behaviors are the best first steps to treat Polycystic Ovary Syndrome (PCOS).

A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Long COVID patients may have hormonal imbalances linked to their symptoms.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.