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This study found that FGF5-/- rabbits exhibited a significant long hair phenotype by prolonging the anagen phase, suggesting FGF5 acts as a negative regulator of hair growth.

In this study, finasteride was found to induce tissue-specific P-glycoprotein activity in the liver and kidney of rabbits after a 14-day treatment period.

This article reviews the challenges of fasting and dietary regimens in producing sustained weight loss and reports no new research findings or results.

Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.

This study confirmed that porcine platelet-rich plasma could commercially replace fetal bovine serum due to its higher growth factor levels and effectiveness as a hair growth promoter comparable to existing serum.

This study highlights that mutations in the MBTPS2 gene can lead to dermatological disorders like IFAP syndrome and severe bone diseases such as X-Linked Osteogenesis Imperfecta, emphasizing the significance of understanding these genetic variants for disease mechanisms and associations.

This article discusses the pulmonary manifestations of Birt-Hogg-Dubé syndrome, noting diagnostic challenges in differentiating it from other lung conditions, and underlines the need for further research on folliculin's role in cyst formation.

Systematic end-of-trial biopsies are the most reliable way to assess outcomes.

This study found significant differences in gene expression, particularly in androgen receptor activity, between men with post-finasteride syndrome and healthy controls, suggesting a potential biological basis for the syndrome.

Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.

The researchers in this study identified molecular mechanisms involved in frontal fibrosis alopecia, highlighting immune response and fatty acid metabolism, and developed a four-gene diagnostic model showing high accuracy in distinguishing affected individuals from controls.

In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.

This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.

This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.

This review covers the history, incidence, and treatment options for pseudofolliculitis barbae and presents new data, but reports no new clinical results.

In this study, researchers identified two person-centered sexual function profiles among women, linked to physical and psychological factors, with PCOS showing greater, though not significant, presence in the dysfunction profile. The dysfunction was associated with higher adiposity and body-image distress.

This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.

This case report identifies a novel maternally inherited MBTPS2 variant associated with an expanded phenotypic spectrum of BRESHECK syndrome, including cytopenias, bone marrow fibrosis, and chronic diarrhea.

In this case report, a novel missense mutation c.1360G>C (p.Ala454Pro) in the MBTPS2 gene was identified in a boy with typical IFAP syndrome and severe atopic features, although no phenotype/genotype correlation was established.

This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.

This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.

This study found that women with polycystic ovary syndrome had significantly higher levels of the protein fetuin-A compared to healthy controls.

This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.

This commentary reviews the post-Finasteride syndrome and argues that while the condition's validity is debated, comprehensive guidelines are needed to address related risks and treatment options; it reports no new clinical results.

This study found that lipid accumulation product (LAP) and free androgen index (FAI) can highly predict liver steatosis in women with PCOS phenotype A.

This study found that autophagy is impaired in Birt-Hogg-Dubé syndrome-associated renal tumors and identified that the FLCN protein interacts with key autophagy components regulated by ULK1.

This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.

Finasteride caused blisters on hands and feet.

This study observed that repeated hair follicle sampling is feasible and reliable for measuring FMR1 mRNA and FMRP in individuals with Fragile X syndrome, supporting its use in longitudinal studies.

This case study reported the first diagnosis of IFAP syndrome in Brazil with molecular investigation, identifying a rare MBTPS2 gene variant and expanding the known mutational spectrum associated with the condition.