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research Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?
This review hypothesizes that excessive facial photo-protection may contribute to frontal fibrosing alopecia by disrupting immunological homeostasis through the aryl hydrocarbon receptor-kynurenine pathway, but it reports no new clinical results.
research Steroid 5α-reductase inhibition by polymethoxyflavones
This study found that among eleven tested polymethoxyflavones, 5-hydroxy-7,4′-dimethoxyflavone was the strongest steroid 5α-reductase inhibitor and suggests potential use for benign prostatic hyperplasia treatment.
research A Novel Mutation in theMBTPS2Gene Resulting in Ichthyosis Follicularis, Atrichia, and Photophobia Syndrome
In this case report, researchers identified a novel homozygous missense mutation in the MBTPS2 gene associated with the mild form of IFAP syndrome in a 7-year-old boy.
research Systemic photodynamic therapy in folliculitis decalvans
In this report, a 26-year-old man with folliculitis decalvans unresponsive to standard treatments experienced significant disease clearance after 25 months of systemic photodynamic therapy, marking the first documented use of this therapy for this condition.
research Platelet-rich fibrin – contemporary approach in aesthetic medicine and dentistry
This review discusses the potential role of platelet-rich fibrin in aesthetic and dental procedures but highlights the need for more rigorous future studies to confirm its effectiveness and safety.
research Bioassay-guided isolation of two antiproliferative metabolites from Pterocarpus indicus Willd. against TGF-β-induced prostate stromal cells (WPMY-1) proliferation via PI3K/AKT signaling pathway
This laboratory study found that PI extract, along with its metabolites Ang and Mac, inhibited cell proliferation and protein expression linked to pathways involved in BPH, suggesting potential for therapeutic use, although the Ang-Mac combination showed no significant effect on apoptosis through the p53 pathway.
research Potential Biomolecule Fisetin: Molecular and Pharmacological Perspectives
This study explores the various properties of the flavonoid fisetin, highlighting its potential therapeutic applications due to its ability to modulate numerous biological pathways, suggesting benefits in conditions like inflammation, cancer, and neurodegenerative diseases.
research Photobiomodulation therapy
This review discusses the state-of-the-art in photobiomodulation therapy for oral and dental applications and emphasizes the need for education, training, and addressing logistical issues for its routine use.
research Eosinophilic pustular folliculitis (Ofuji’s disease) without macroscopic pustules
This case report describes three instances of eosinophilic pustular folliculitis lacking visible pustules, which histopathology confirmed involve eosinophilic infiltration around hair follicles.
research Le point de vue du pathologiste concernant l’étude PCPT
research Plumbagin, a Natural Compound with Several Biological Effects and Anti-Inflammatory Properties
This review summarizes the mechanisms by which Plumbagin, a naphthoquinone derived from plants, may impact inflammation and explores its potential biological effects, highlighting areas that require further comprehensive research before considering it for therapeutic use.
research Flexible bioelectronic innovation for personalized health management
This paper discusses the recent advancements and challenges of flexible bioelectronics in personalized health management and cancer therapy, but reports no new studies or results.
research Comment on “The post-finasteride syndrome: possible etiological mechanisms and symptoms”
Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.
research A Retrospective Study of Frontal Fibrosing Alopecia from North-East India
This study from North-East India analyzed 21 cases of frontal fibrosing alopecia, noting a high prevalence in post-menopausal women and distinct histological features such as perifollicular lymphocytic infiltrate and hydropic degeneration.
research Follicular Psoriasis: A Case Report and Review of Literature
In this case report, a 31-year-old diabetic and obese male was diagnosed with follicular psoriasis, a rare variant characterized by scaly follicular papules, using dermoscopy and histopathology; treatment with topical mometasone furoate and oral levocetirizine led to complete lesion resolution within a month.
research Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies
This study developed a reliable HPLC-UV/Vis method to determine aluminum phthalocyanine chloride in skin, supporting its use in skin permeation studies for photodynamic therapy of cutaneous tumors.
research Use of Leukocyte Platelet (L-PRF) Rich Fibrin in Diabetic Foot Ulcer with Osteomyelitis (Three Clinical Cases Report)
This study observed that fibrin rich in leukocytes and platelets (L-PRF) might effectively heal diabetic foot ulcers with osteomyelitis, showing positive preliminary results in all three patients treated.
research Anti-BPH lignans from Urtica triangularis subsp. pinnatifida (Hand.-Mazz.) C.J.Chen
This study found that compound 4 from Urtica triangularis subsp. pinnatifida exhibited stronger anti-BPH activity against BPH-1 cells with an IC50 of 79.75 μM compared to finasteride's IC50 of 91.8 μM, while compounds 1, 2, and 5 showed moderate activity.
research The Human Innate Immune Protein Calprotectin Elicits a Multimetal Starvation Response in Pseudomonas aeruginosa
This study found that multimetal starvation by the immune protein calprotectin triggers unique regulatory responses in Pseudomonas aeruginosa, beyond those seen with individual metal shortages.
research Use of facial care products and frontal fibrosing alopecia: Coincidence or true association?
This study in Asian females found that higher use of moisturizers and sunscreen among FFA patients may reflect appearance concerns rather than indicating a direct link to the disease mechanism.
research Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: a single‐center, retrospective study
In this study, FAPD was characterized in a Chinese population by perifollicular mast cell infiltration, suggesting young individuals may be at higher risk than previously thought.
research Differential diagnoses of pseudolymphomatous folliculitis: considerations as regards one case
This case report discusses a rare instance of pseudolymphomatous folliculitis in a 19-year-old man, highlighting the challenge in diagnosing PLF due to its low clinical suspicion index and variable initial clinical diagnoses.
research Method of chest compression for infants in a single rescuer; evaluation of chest compression technique and new device
This study found that structural changes in the stroma surrounding hair follicles and skin laxity are associated with the appearance of large pores, regardless of ethnicity or age.
research PA13 A hair’s breadth from misdiagnosis
This case report highlights the diagnosis of folliculotropic mycosis fungoides in a 15-year-old boy with atypical skin and hair follicle changes, a rare occurrence in pediatric patients.
research Folliculotropic mycosis fungoides following renal transplantation
This case report describes a 46-year-old man who developed folliculotropic mycosis fungoides, a form of post-transplant lymphoproliferative disorder, following renal transplantation.
research 560 The molecular mechanism of PCE-DP, a novel brightening active ingredient
This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.
research Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist
In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.
research Industrial-scale processing of activated platelet-rich plasma from specific pathogen-free pigs and its effect on promoting human hair follicle dermal papilla cell cultivation
This study found that porcine platelet-rich plasma can be a commercially viable replacement for fetal bovine serum with similar effectiveness in promoting human hair follicle cell growth.