108 citations
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April 2004 in “Medicinal Research Reviews” This review discusses the medicinal chemistry of steroid sulfatase inhibitors for estrogen- and androgen-dependent disorders but reports no new clinical results.
September 2026 in “Angewandte Chemie International Edition” In this study, SEU-302, a newly synthesized covalent organic framework, demonstrated potent photodynamic antibacterial effects, showing effective elimination of Staphylococcus aureus, wound healing promotion, and inflammation reduction both in vitro and in vivo, highlighting its therapeutic promise against bacterial infections.
2 citations
,
January 1968 in “PubMed” This study found that X-irradiation causes hair dysplasia through two mechanisms influenced by oxygen, and cystamine injections after irradiation enhance this effect.
7 citations
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January 1995 in “Journal American Society of Mining and Reclamation” This review discusses the forms of selenium and sulfur in soil, their plant absorption, and risks of toxicity to livestock, emphasizing selenium's role in selenosis and sulfur's link to polioencephalomalacia in ruminants; it reports no new experimental results.
March 1990 in “Journal of Dermatological Science” January 1995 in “Seoul National University Open Repository (Seoul National University)” This study found that skin sulfhydryl oxidase plays a role in keratinization and may contribute to skin's protective functions, with its expression influenced by irritants and differentiation modifiers.
25 citations
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May 2003 in “Expert Opinion on Therapeutic Patents” This review examines patents and publications on steroid sulfatase inhibitors since 1999 and reports no new clinical results, highlighting their potential for treating estrogen- and androgen-driven conditions.
April 2024 in “Advances in Redox Research” In this study, researchers found that polysulfides in human hair keratin contribute to hair strength and antioxidant capacity, with sulfur supplementation enhancing hair strength and cuticle structure amid oxidative stresses such as UV radiation.
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
1 citations
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July 1990 in “European Journal of Pharmacology” 12 citations
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July 1964 in “Archives of Dermatology” This study found that neither a single application nor prolonged exposure to selenium sulfide had a significant effect on hair growth or rest phase percentages.
7 citations
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March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
5 citations
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October 2001 in “British Journal of Ophthalmology” This abstract describes the initial success of intralesional cidofovir for SCC treatment and states that it has not shown systemic toxicity, but it does not report new clinical trial results.
February 2025 in “Biomimetics” This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.
This study found that exposure to Prussian Blue caused significant detachment of cuticle segments from the hair shaft in both new and aged human hairs.
January 2026 in “Molecules” In this study, the novel thiol-Michael click perming molecule, MA2-CySS, achieved repeatable perming with reduced oxidative damage, preserving hair keratin's structure while maintaining efficiency comparable to traditional oxidative methods.
18 citations
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January 2008 in “Sen'i Gakkaishi” This study observed that repeated perm treatments decrease disulfide bonds in hair due to their conversion largely into cysteic acid, affecting the waving efficiency depending on the reduction agent used.
1 citations
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January 2003 in “Expert Opinion on Therapeutic Patents” This review discusses the development and potential therapeutic applications of steroid sulfatase inhibitors for hormone-dependent disorders and cognitive dysfunction, reporting no new clinical results.
3 citations
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January 1995 in “PubMed” This study found that selenium therapy could normalize metabolic and endocrine markers and improve clinical outcomes in cystic fibrosis patients, with stable benefits when administered at a lower dosage over a year.
14 citations
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September 2016 in “Journal of Photochemistry and Photobiology B Biology” This study observed that mercury-lamp irradiation may cause cleavage of disulfide bonds in keratins of white hair, leading to the formation of thiols in laboratory settings.
January 2008 in “Chinese Journal of Spectroscopy Laboratory” This study utilized a fluorescence probe to evaluate cysteine formation on hair fibers, finding that optimal fluorescence emission occurred at pH 4.5.
16 citations
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September 1999 in “Journal of Investigative Dermatology Symposium Proceedings”
September 2023 in “Food and chemical toxicology” In this study on Sprague-Dawley rats, 0.60 mg/kg doses of L-Se-methylselenocysteine and sodium selenite were associated with liver toxicity and reduced sperm motility, while Se-enriched peptides showed no observable adverse effects up to 0.60 mg/kg.
1 citations
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January 2017 in “Chinese Journal of Organic Chemistry” Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.
8 citations
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January 1968 This study found that high concentrations of dimethyl sulfoxide are needed to cause significant swelling in hair fibers, though the swelling is reversible, unlike the effects on skin.
66 citations
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September 1982 in “Biochemical Pharmacology” This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.
January 2015 in “Journals & Books Hosting (International Knowledge Sharing Platform)” This study synthesized and evaluated five 6-mercaptopurine derivatives for anticancer activity against three cancer cell lines, detailing the promising results of compound 1.
March 2010 in “International Journal of Cosmetic Science” This study found that oxidative treatment with peracetic acid dissociates some disulfide bonds in human hair fibers while maintaining the crystalline structure, suggesting different mechanisms stabilize different regions of intermediate filaments.
13 citations
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January 1997 in “Biochemical Pharmacology” This study found that human liver dehydroepiandrosterone sulfotransferase (DHEA ST) catalyzes the sulfate conjugation of minoxidil, indicating another pathway contributing to its metabolism in humans.
12 citations
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December 1962 in “Journal of Investigative Dermatology”