November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study examined the thermal conductivity of human hair using the Modified Transient Plane Source method, highlighting how frequent thermal, mechanical, and chemical treatments can damage hair by weakening its structure, particularly through changes in keratin that reduce elasticity.
3 citations
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March 2005 in “Iranian Journal of Pharmaceutical Sciences” This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.
December 2024 in “Tropical Journal of Natural Product Research” This study observed that CTUMP's Herb shampoo significantly improved hair growth and density in mice compared to a saline solution, though it was less effective than minoxidil in promoting follicle development.
In this study, Biofield Energy Healing significantly increased the proliferation of human hair follicle dermal papilla cells in vitro, suggesting potential as a hair growth promoter.
September 1998 in “Hair transplant forum international” This article reflects on the author's experiences and observations in the field of hair restoration over the past 12 years but provides no new research findings.
1 citations
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June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.
161 citations
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April 2006 in “Journal of Investigative Dermatology” Liposomes with certain properties can effectively deliver drugs deep into hair follicles.
May 2026 in “Journal of Cutaneous and Aesthetic Surgery” In this study, researchers developed a novel bio-enhanced hair transplant technique that, among 10 patients, provided aesthetically pleasing outcomes with minimal downtime, linear increases in density over nine months, and uneventful donor area healing with no visible scarring.
May 1995 in “Journal of Investigative Dermatology” Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.
26 citations
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January 2016 in “Annals of Dermatology” This study found that Ecklonia cava polyphenols increased human dermal papilla cell proliferation and extended hair shaft length in vitro and ex vivo, suggesting potential as a therapeutic candidate for hair loss.
This study examined the effects of one-time versus two-time hair bleaching in people from Padang City, finding that two-time bleaching significantly increased hair dryness and reduced elasticity compared to one-time bleaching, emphasizing the importance of considering bleaching frequency for hair health.
6 citations
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June 2019 in “Skin Research and Technology” In this study, finasteride treatment for two years did not significantly reverse miniaturized hair follicles in men with male pattern hair loss, challenging the "reversal hypothesis" as 79 out of 113 miniaturized hairs remained unchanged.
April 2023 in “Journal of Investigative Dermatology” In this study, several photobiomodulation devices showed statistically significant improvement in hair growth for patients with androgenetic alopecia, with varying efficacy between devices and genders.
1 citations
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November 2023 in “Cosmetics” This study found that washing hair with surfactants reduces the internal density of hair due to cuticle lifting, and suggests that a cuticle-sealing strategy can inhibit this effect and maintain hair homeostasis.
January 2022 in “Stem cell biology and regenerative medicine” This review discusses advances in using tissue engineering to improve the inductivity of dermal papilla cells for hair follicle restoration and reports no new clinical results.
February 2022 in “Pakistan Journal of Medical and Health Sciences” This study reported that finasteride administered at 2.5 mg/day was clinically effective in 62% of women with female pattern hair loss, with greater efficacy observed in those who were premenopausal or had a lower Ludwig score.
September 2025 in “Polymer Korea” In this study, a parsley-derived n-hexane fraction formulated into a coconut oil-based nanoemulsion demonstrated significant hair regrowth comparable to 3% minoxidil, with near-complete coverage by day 17, suggesting potential as a topical hair growth treatment.
1 citations
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January 2020 in “Seoul National University Open Repository (Seoul National University)” This study found that a phosphodiesterase 3 inhibitor promoted hair growth in human dermal papilla cells and stimulated anagen induction in mice, suggesting potential as a treatment for alopecia.
This study found that isolated human scalp hair follicles express PGE2 genes and EP2 protein, suggesting PGE2 may play a crucial role in regulating hair growth.
3 citations
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September 1989 in “Journal of Investigative Dermatology” This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.
316 citations
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June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.
September 2025 in “International Journal of Scientific Research” This study found that platelet-rich plasma therapy was more effective than Minoxidil 5% in improving hair density, hair thickness, and patient satisfaction in men with androgenetic alopecia.
9 citations
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January 1983 in “Journal of Chromatography B Biomedical Sciences and Applications” This study found that enzyme activity related to cancer induction by polycyclic aromatic hydrocarbons can be increased by using a shampoo containing crude coal tar and significantly inhibited by imidazole compounds in human hair follicles.
October 2023 in “Journal of the Endocrine Society” In this study, estetrol (E4) treatment was associated with increased hair growth in ex vivo human hair follicles, suggesting its potential as a treatment for hair loss disorders.
4 citations
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July 2024 in “Animals” The researchers reported an optimized depilation procedure using cold wax and an extra skin protection step that minimizes injury in mice, revealing similar hair cycle kinetics across strains and supporting the use of Sv129 and B6129F1 mice in hair growth studies.
February 2025 in “Brazilian Journal of Hair Health” This study found that multiparametric ultrasound effectively detects real-time scalp changes caused by vasoconstrictive cosmetic agents, demonstrating its potential as a non-invasive tool for evaluating trichological treatments.
1 citations
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December 2017 in “JAMA Facial Plastic Surgery” This study found that both PHDPE and ePTFE hair-bearing scaffolds were well tolerated in a rat model, with minimal infection or extrusion, though artificial hair showed progressive loss over time.
7 citations
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April 2021 in “Journal of advanced pharmaceutical technology & research” This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.