Scalp Analysis with Multiparametric Ultrasound Before and After Application of Cosmetic with Vasoconstrictor Active

This study demonstrates the effectiveness of multiparametric ultrasound (MPU) in evaluating the impact of a vasoconstrictive cosmetic active on scalp physiology. The fast-permeation formulation resulted in a significant reduction in vascular perfusion and a 32.5% increase in dermal stiffness, indicating localized vasoconstriction. The slow-permeation formulation showed a gradual but sustained effect, with an increase in the resistance index from 0.40 to 0.64 and a 20% increase in dermal stiffness. These findings suggest that MPU is a valuable non-invasive tool for real-time monitoring of cosmetic and pharmacological effects on the scalp, potentially becoming a standard method in trichological treatment evaluation.