October 2024 in “Cosmetics” In this study, reducing agents like ammonium thioglycolate, L-cysteine, and sodium sulfite in shampoo effectively decreased hair flyaway and frizz without causing damage, as no critical hair damage was observed in structural and tensile strength assessments.
January 2024 in “Molecules (Basel. Online)” In this study, researchers examined juglone's potential as a restoring agent for hair keratin damaged by permanent or bleaching treatments, finding that juglone formed Michael adducts with cysteine residues, leading to a more regular hair surface as observed via IR spectroscopy and SEM analysis.
53 citations
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July 2016 in “Cosmetics” This study reviews the biology and cosmetic treatment of hair, emphasizing future advancements in safer, more effective procedures to meet consumer needs for hair care.
5 citations
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February 2022 in “Acta Biomaterialia” This review highlights the potential of nanotechnology-based formulations in hair care and treatment, emphasizing how these innovative materials can enhance the stability, efficacy, and safety of active compounds while addressing the limitations of conventional formulations.
June 2025 in “Cell Metabolism” This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.
63 citations
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February 2017 in “ACS biomaterials science & engineering” In this study, polydopamine emerged as a safe and effective alternative to traditional hair dyes like PPD for dyeing gray hair permanently, showing resistance to detergents and causing less toxicity and hair loss in mice.
29 citations
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January 2020 in “Journal of Burn Care & Research” This article discusses the challenges and lack of progress in improving burn care outcomes for patients aged 65 and older, highlighting the urgent need for tailored treatment protocols and better understanding of their long-term care needs.
20 citations
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December 2012 in “Journal of molecular structure” This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.
18 citations
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February 2023 in “eLife” This study indicates that innate lymphoid cells-type 1 may provoke alopecia areata by disrupting hair follicle immune privilege and inducing characteristic lesions, challenging the view that alopecia areata is purely an autoantigen-dependent, T cell-driven condition.
18 citations
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June 2019 in “Clinical research in dermatology” This review discusses psychological impacts associated with facial acne, noting that high levels of anxiety and depression among these patients are not linked to oxidative stress, and reports no new clinical results.
15 citations
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December 2018 in “International journal of environmental research and public health/International journal of environmental research and public health” This study observed that Epigallocatechin-3-gallate (EGCG) can inhibit phosphorylation of STAT1 and reduce a specific subset of immune cells in vitro and ex vivo, suggesting a potential role in maintaining immune privilege in alopecia areata.
13 citations
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October 2021 in “International Journal of Molecular Sciences” In this study, an immortalized MSC line from human adipose tissue showed potential for applications in regenerative medicine and inflammatory diseases through production of active factors, demonstrated in vitro.
9 citations
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September 2022 in “Journal of Clinical Investigation” In this study, mouse models of 22q11.2 deletion syndrome showed that growth issues in small embryonic thymuses were linked to mesenchymal cells, which could be corrected by substituting with normal mesenchyme.
8 citations
,
November 2024 in “EMBO Molecular Medicine” In this study, researchers found that disrupting EGFR signaling in mice led to increased inflammation and hair follicle damage but that inhibiting the JAK-STAT1 pathway could restore hair growth and skin function.
7 citations
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November 2022 in “International Journal of Molecular Sciences” This study found that both Japanese male and female hair darkens with age, with significant sex differences in melanin composition and melanosome morphology influencing hair color.
7 citations
,
August 2024 in “Journal of Functional Biomaterials” This review concludes that platelet-rich plasma injections significantly improve knee joint function compared to alternative treatments in managing knee osteoarthritis.
6 citations
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December 2022 in “Cell reports” This study found that feeding mice a high-fat diet with fish oil leads to hair loss through a mechanism involving omega-3 fatty acids and TNF-α signaling, with epidermal fatty acid binding protein playing a key role.
4 citations
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January 2023 in “Skin health and disease” This study shows that in a mouse model of Alopecia Areata, selective JAK1 inhibition facilitated hair regrowth and inflammation resolution while potentially offering a better safety profile compared to pan-JAK inhibition.
3 citations
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August 2024 in “The Journal of Cell Biology” This study demonstrated that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments with different biophysical properties.
3 citations
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September 2023 in “Stem Cell Research & Therapy” In this study, researchers successfully generated functional and long-lived melanocytes from human embryonic stem cells, demonstrating their biocompatibility and high engraftability in mice, which may aid in developing treatments for pigmentary skin disorders.
3 citations
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January 2022 in “Scientific Reports” This study found that SAMiRNA-AR68, a nanomedicine targeting androgen receptor mRNA, increased hair counts in androgenetic alopecia patients with no observed side effects.
July 2026 in “Preprints.org” In this study, incorporating a novel amino acid compound into a hair-straightening formulation improved humidity-resistant straightening and enhanced the surface and mechanical properties of hair fibers, including increased bending stiffness, reduced friction, and better shape retention under high temperature and humidity conditions.
May 2026 in “Science Advances” This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.
May 2026 in “Nature Communications” In this study, researchers identified that keloid fibroblasts respond to neurotransmitters from catecholaminergic nerves by producing bone matrix proteins, mediated by β1-adrenergic receptor activation, leading to fibro-osseous reprogramming; blocking this signaling in a rodent model prevented the development of keloid-like pathology.
January 2026 in “Molecules” In this study, the novel thiol-Michael click perming molecule, MA2-CySS, achieved repeatable perming with reduced oxidative damage, preserving hair keratin's structure while maintaining efficiency comparable to traditional oxidative methods.
This study found that acute stress can cause rapid hair loss by triggering necrosis in hair follicle cells and initiating autoimmunity, revealing a mechanism where stress-induced nerve activity leads to tissue damage and immune system activation.
November 2025 in “Advanced Science” In this study, researchers found that a cold atmospheric plasma-activated hydrogel containing interleukin-2 significantly enhanced hair regeneration in a depilated mouse model, promoting larger hair follicles and faster hair growth phase transition, suggesting it as a potential treatment for hair loss.
August 2025 in “BMC Pharmacology and Toxicology” The LTF gene may help predict and manage nonspecific orbital inflammation.
May 2025 in “Clinical Cosmetic and Investigational Dermatology” In this clinical study, the researchers found that a standardized wheat polar lipid complex, in both oil and powder form, significantly reduced hair shedding and improved hair growth in 99 women with acute telogen effluvium over 56 to 84 days.
February 2025 in “Biomimetics” This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.