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Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Improving skin barrier and using antifungal treatments can help manage dandruff.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Best hair growth results from combining finasteride and minoxidil.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Minoxidil promotes hair growth but stops working when discontinued.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

New treatments for male hypogonadism are effective and should be personalized.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Advanced human skin models improve drug development and could replace animal testing.

Traditional Chinese medicines with heavy metals can cause severe poisoning.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.