April 2025 in “Journal of Cosmetic and Laser Therapy” This study found that QR678 Neo® significantly enhanced hair regrowth, density, and shaft diameter in males with advanced androgenetic alopecia undergoing hair transplant surgery, compared to a conventional method, making it a promising adjunct treatment option.
April 2018 in “Journal of Investigative Dermatology” This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.
March 2026 in “Frontiers in Pharmacology” This study reviews new treatments for androgenetic alopecia, including cell-derived exosomes and investigational drugs, which show potential to improve hair density and quality but require more rigorous and standardized trials to confirm efficacy and safety.
December 2020 in “Èffektivnaâ farmakoterapiâ” In this study, researchers observed that a new peptide complex helped increase hair density in postmenopausal patients with female-type hair loss by promoting the transition of hair follicles from a resting stage to a growth stage.
April 2024 in “Cosmetics” This review highlights the use of microneedling devices and patches to deliver cosmetic agents through the skin, noting their applications in skin rejuvenation and safety considerations such as potential skin irritation and infection.
January 2015 in “Hair therapy & transplantation” This review discusses natural and botanical products examined for treating alopecia and reports no clinical results; the authors note growing research interest in these treatments.
33 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.
1 citations
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November 2022 in “International journal of trichology” In this case study, a 25-year-old female with premature hair graying achieved over 90% conversion of gray hair to black hair after 5 months of treatment with a topical peptide solution and hair supplements.
6 citations
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May 2020 in “Pharmacology Research & Perspectives” This study in rats found that a new hydroxypropyl-β-cyclodextrin formulation of minoxidil reduced the adverse cardiovascular and proliferative effects seen with traditional minoxidil solutions.
5 citations
,
December 2023 in “Materials” This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.
86 citations
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March 2018 in “ACS Biomaterials Science & Engineering” This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.
5 citations
,
January 2017 in “Elsevier eBooks” This review focuses on the roles of amino acids, peptides, and proteins in cosmetics, highlighting their importance in skin health and their potential for development in personal care products due to their unique properties and biocompatibility.
July 2024 in “International journal of agriculture and food sciences research.” This study found that a hair conditioner using peptides from Pneumatophorus japonicus heads improved damaged hair's structure, gloss, and smoothness more effectively than a commercial wheat protein conditioner by increasing amino acid content and interacting with hair keratin.
January 2018 in “journal of applied pharmaceutical science” Biomimetic peptides improved hair growth and increased growth factors in hair follicles for hair loss patients.
2 citations
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July 2021 in “Dermatologic Therapy” This case study reports a 58-year-old woman experiencing pressure-induced alopecia with concomitant acute telogen effluvium after severe COVID-19, suggesting a potential link between prolonged hospitalization and hair loss.
41 citations
,
September 2021 in “Materials” This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.
This article introduces REVVup Hair Therapy as an alternative to surgery for early-stage hair loss but reports no new clinical findings.
September 2005 in “Journal of Investigative Dermatology” This study found that ferulic acid effectively stabilized vitamins C and E in a topical solution, doubling skin photoprotection against solar-simulated irradiation, which may help in preventing photoaging and skin cancer.
9 citations
,
October 2018 in “Elsevier eBooks” This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.
39 citations
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April 2019 in “Journal of Biomaterials Science, Polymer Edition” This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.
April 2016 in “Journal of Investigative Dermatology” This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
3 citations
,
April 2021 in “Journal of Cosmetic Dermatology” Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.
47 citations
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January 2017 in “RSC Advances” Keratin peptides can change hair shape gently without harsh chemicals.
38 citations
,
June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” In this study, the RADA-PRG hydrogel enhanced SKP proliferation, survival, and gene expression, effectively supporting hair follicle regeneration in mice.
29 citations
,
April 2020 in “Biomolecules” The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.
14 citations
,
January 2012 in “Proteins” This study's molecular dynamics simulations suggest that electrostatic interactions mainly stabilize peptide binding to human hair keratin, with the protein's dielectric constant significantly affecting free energy calculations.
February 2024 in “Research Square (Research Square)” In this study, researchers applied Strat-M® membrane to assess the in vitro transdermal properties of collagen peptides, finding a high correlation with results from mouse skin and suggesting that Strat-M® can effectively replace excised mouse skin in transdermal experiments.
13 citations
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November 2014 in “Pediatric emergency care” This study reports that the ingestion of a small amount of topical minoxidil by a child resulted in significant intoxication, suggesting the need for enhanced child-resistant packaging.
December 2022 in “Deleted Journal” In this study, topical application of keratin extract from wool promoted hair growth in mice by reducing the time for initiation and completion of growth phases and improving hair quality.
May 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the peach gene CTG134, involved in auxin-ethylene interactions, plays a role in hormonal regulation during root hair formation in Arabidopsis and tobacco.