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This study found that the XEDAR receptor can activate the non-canonical NF-kB pathway involving p100 processing, which is regulated by interactions with TRAF proteins and specific kinases.

This study demonstrates that bioequivalence for proposed 50-mg ritlecitinib capsules versus clinical 100-mg capsules can be supported using a PBPK model-based biowaiver, achieving over 90% probability of success.

This review discusses the development of Janus kinase inhibitors for dermatologic diseases and reports no new results; the authors note the need for further research on their efficacy and safety.

This article argues that the promissory discourse in the anti-ageing treatments market exploits societal anxieties about ageing, but its long-term sustainability is questionable as many promises remain undeliverable.

This study suggests that minoxidil may serve as a suitable reference drug for high permeability classification in the Biopharmaceutics Classification System due to its consistent permeability across different intestinal segments and pH levels.

This study found that the pH dependency of rat steroid 5α-reductase type II isozyme significantly affects its kinetic properties, including Vmax and Km, suggesting past discrepancies in literature may arise from these pH variances during assays.

This study found that 1-butyl-3-methylimidazolium tetrafluoroborate is the optimal ionic liquid solvent for extracting quercetin from Nothopanax scutellarium leaves.

This joint position paper by several Polish medical societies examines guidelines and recommendations for managing conditions like obesity, hypertension, and liver disease, underscoring the importance of a collaborative, interdisciplinary approach in treatment. Results are not explicitly reported.

In this study, adding TPGS to a minoxidil formulation improved local retention and reduced systemic absorption in certain solvent mixes, particularly with a balance of alcohol and PEG 400.

In this study, deuruxolitinib and baricitinib showed promising efficacy in treating alopecia areata, but effectiveness varied with dosage and further trials are needed to confirm these results.

In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.

In this study, researchers developed a new photoactivatable Cre recombinase mouse model, DiLiCre, which allows precise light-induced genetic modifications and cell tracing, demonstrating its effectiveness for advancing biological and biomedical research.

This study reported that new drugs, despite lower specificity compared to certain immunobiological therapies, are effective across various challenging dermatological diseases, such as psoriasis, psoriatic arthritis, atopic dermatitis, alopecia areata, and vitiligo.

This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.

This case report describes a 29-year-old Japanese-Paraguayan man who experienced a relapse of leprosy 14 years after initial treatment, presenting with severe pain and skin lesions but no sensory impairment.

This study found that adding low-level laser therapy to conventional treatment for canine acral lick dermatitis significantly increased hair growth compared to conventional therapy alone, but did not significantly reduce licking behavior.

This study found that PRP may effectively reduce TMJ pain and improve jaw function and quality of life in young adults with mild TMD.

This review highlights that several clinical and epidemiological studies link a diet high in terpenoid compounds with a decreased risk of prostate cancer, supporting the potential use of terpenoids as therapeutic ingredients in treating this disease.

This review highlights that although mangiferin, a polyphenol from the mango tree, faces challenges like low solubility and bioavailability, delivery vehicles such as nanoparticles and complexes have the potential to enhance its therapeutic effectiveness in treating various diseases.

This study found that red galangal rhizome simplicia extract demonstrated the strongest antibacterial effect against Propionibacterium acnes among tested extracts, achieving a 31.5 mm inhibitory zone at a 20% concentration.

This review covers the use of JAK inhibitors in treating various dermatological conditions, emphasizing their potential while noting ongoing safety concerns with oral treatments; no new clinical results are provided.

This article reviews the role of the JAK-STAT pathway in inflammatory skin diseases and considers the therapeutic benefits of JAK inhibitors, presenting them as promising treatments but reports no new experimental results.

This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.

This case study details a 44-year-old woman with rheumatoid arthritis and systemic lupus erythematosus who developed hypereosinophilic asthma and was initially treated as ANCA-negative eosinophilic granulomatosis with polyangiitis. Her condition, eventually classified as HASM, underscores the need for evaluating EGPA-spectrum disorders in similar scenarios.

This study demonstrated that RNA-seq can effectively expand hair follicle transcriptomic profiling in a multi-center study, offering deeper insights than blood transcriptomics alone.

This abstract serves as a promotional notice for a book titled "Essentials of Food Science and Nutrition" by several authors, offering it for sale at a low price, but does not report any research results.

This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.

This study found that the M5 isolation method for human dermal papilla cells significantly improved attachment efficiency, proliferative capacity, and trichogenic potential, providing an optimized strategy for scalable manufacturing in hair regeneration therapies for conditions like alopecia.

In this case report, a female patient with both psoriasis and lichen planus initially responded to acitretin and topical mometasone but experienced a relapse after stopping the treatment. The authors reported marked improvement within 3 months after switching to upadacitinib, aiming to guide clinical decision-making.

This report details a six-month internship experience, split between hospital and community pharmacy settings, which enhanced practical skills and theoretical knowledge in pharmaceutical care and highlighted the pharmacist's role in ensuring safe medication use.