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This expert opinion article presents insights from dermatologists and aesthetic physicians on using polynucleotides (Rejuran®) for skin hydration, rejuvenation, structural support, barrier repair, and scar remodeling, noting their favorable safety profile but highlighting the need for more robust evidence and research.

In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.

This policy brief found that post-drug syndromes are under-recognized in current pharmacovigilance systems, leading to inadequate risk assessments and prolonged patient harm from persistent drug-induced conditions.

This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This review discusses the development and potential therapeutic applications of adenosine receptor agonists and positive allosteric modulators, noting that while many clinical trials have been unsuccessful, initial results for new compounds are promising.

This meta-analysis suggests that local injection of platelet-rich plasma for androgenic alopecia is associated with an increased number of hairs and some increase in hair thickness, though larger studies are needed for confirmation.

This article reviews innovations in hair cosmetics, focusing on esthetic procedures and products in the Indian market, and reports no new experimental findings.

This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.

This meta-analysis reported that platelet-rich plasma injections for androgenetic alopecia may increase hair number and thickness locally, but further studies are needed to establish their overall effectiveness.

This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.

This review detailed the types and mechanisms of injectable "skin boosters" and evaluated their effectiveness and safety for mitigating age-related skin changes, providing insight into their use in contemporary dermatological practice.

This research review found that platelet-rich plasma treatment generally produced successful hair regrowth in both androgenetic alopecia and alopecia areata, despite study differences that limited direct statistical comparison.

This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.

This study found that alginate beads containing monoolein demonstrated promising potential for managing wet wounds by better absorbing excess exudate and delivering adenosine locally, favoring drug localization in damaged porcine skin compared to an aqueous solution without affecting skin viability.

This study reported that fibrosing alopecia in a pattern distribution can occur in patients of color, with clinical and histopathological features allowing for an accurate differential diagnosis.

This review outlines recent research on platelet-rich plasma, alone or combined with other therapies, for managing hair loss disorders, and discusses future prospects without reporting new clinical findings.

This review discusses the use of platelet-rich plasma for treating female androgenetic alopecia, reporting that it shows high patient satisfaction and improved quality of life in affected women.

This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.

In this case report, the authors describe a partial androgen insensitivity syndrome patient with a novel AR gene mutation, highlighting challenges in gender assignment decisions for infants with partial AIS.

This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.

In this article, the authors describe a successfully treated case of a newborn with ichthyosis using a neonatal protocol involving an incubator with controlled temperature and humidity, sepsis prevention, eye protection, and emollient care without keratolytics during the early neonatal period.

This study discusses how polynucleotide-based cosmetic products can improve aging skin in patients with particular morphotypes by restoring cellular metabolism, enhancing microcirculation, and promoting intracellular matrix remodeling, offering potential benefits for reversing chrono- and photo-aging and aiding tissue recovery after cosmetic or surgical procedures.

This study highlights the underexplored allergenic potential of Trichophyton rubrum, a dermatophyte, which can trigger IgE-mediated allergic reactions and a Th2 immune response shift, underscoring the need for its inclusion in diagnostic panels and further research for treating chronic mycoses and related allergies.

This study conducted among sex workers in Kostanay reported a low HIV prevalence of 0.8% but a high syphilis rate of 15.6%, highlighting significant social risks and emphasizing the need to expand pre-exposure prophylaxis and prevention programs.

This narrative review highlights recent advancements in anti-ageing cosmetic procedures, emphasizing personalized interventions that improve patient outcomes and quality of life. The review synthesized evidence from 144 articles to assess the effectiveness and potential side effects of surgical and non-surgical techniques for facial rejuvenation.

In this retrospective study, researchers found that fungal infections, xerosis, eczematous dermatitis, and seborrheic dermatitis were the most common dermatological findings among patients with Parkinson's disease, Multiple Sclerosis, and Amyotrophic Lateral Sclerosis, with significant intergroup differences observed.

This systematic review and meta-analysis found that platelet-rich plasma (PRP) therapy is effective in increasing hair density and reducing hair loss for alopecia, with variations in response based on activation status.

This study reported that a novel filler, BM-PHA, demonstrated similar efficacy and safety to Restylane Perlane in treating moderate to severe nasolabial folds over 24 weeks, showing only minor local side effects and similar improvements in wrinkle severity scores between the two treatments.

This review suggests that platelet-rich plasma therapy shows promise for androgenetic alopecia and may be effective for some alopecia areata and cicatricial alopecia cases, but more robust trials are needed.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.