37 citations
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June 2011 in “Journal of The American Academy of Dermatology” This study demonstrates that sebaceous gland loss is a common early feature in primary scarring alopecia and suggests that inflammation of sebaceous glands or ducts may contribute to follicular damage.
35 citations
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July 2022 in “Frontiers in Cell and Developmental Biology” This review discusses the role of mTOR signaling in the epidermis, emphasizing its importance in skin processes like barrier formation and wound repair, and reports no new experimental results.
18 citations
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September 1990 in “Veterinary Dermatology” This study in SPF lambs found that primary and secondary orf virus infections trigger similar skin responses, but the primary infection caused a more severe and prolonged reaction.
16 citations
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November 2022 in “American Journal of Clinical Dermatology” 9 citations
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May 2021 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study suggests that topical minoxidil may be a promising treatment for isolated autosomal recessive woolly hair due to LIPH mutations, although effective treatments are not yet established.
4 citations
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November 2024 in “Anais Brasileiros de Dermatologia” This study reviews current research to better understand how various environmental and lifestyle factors, collectively known as the exposome, impact hair health and aging, acknowledging that the detailed mechanisms remain partially understood.
3 citations
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September 2017 in “Archives of dermatological research” Early diagnosis and tailored treatments are crucial for managing ichthyosis syndromes with hair abnormalities.
2 citations
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May 2021 in “Journal of the Endocrine Society” This study found that in men with high genetic risk factors for polycystic ovary syndrome, there was an associated increase in obesity, type 2 diabetes, coronary artery disease, and androgenic conditions, suggesting these genetic factors can act independently of ovarian function.
1 citations
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January 2019 in “Turk Dermatoloji Dergisi” This study found that oxidative stress, measured through thiol/disulfide balance, is closely linked to the pathogenesis of telogen effluvium.
August 2026 in “Clinical Cosmetic and Investigational Dermatology” This review synthesizes current knowledge on acral vitiligo, highlighting its treatment resistance, psychosocial impact, and emerging therapies like JAK inhibitors, while identifying knowledge gaps and future research directions.
December 2025 in “Mycoses” In this study involving a murine skin infection model, researchers found that the Trichophyton mentagrophytes strain TIMM 2789, specific to rodents, induced typical symptoms of superficial dermatophytosis, while revealing that the fungal gene SUB6 is not essential for virulence.
November 2025 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study identified elevated CD25 on secreting CD4 regulatory T cells as a genetic risk factor for androgenetic alopecia, with certain plasma proteins acting as mediators in this causal relationship.
November 2025 in “The Journal of Immunology” In this study, researchers observed elevated levels of epidermal γδ T cells, keratinocytes, and an upregulation of the BST2 gene among immune cells in C3H/HeJ mice with alopecia areata, suggesting a potential role in disease pathogenesis.
September 2025 in “Cutaneous and Ocular Toxicology” In this study, researchers found no significant differences in serum levels of ferritin, folate, vitamin B12, vitamin D, or thyroid function between patients with scarring alopecia and healthy controls, suggesting these factors may not play a major role in the disease's pathogenesis.
May 2025 in “International Journal of Dermatology”
This review discusses how herbal therapies may help manage alopecia and improve quality of life, noting their potential benefits like lower cost and fewer side effects, but emphasizes that more clinical studies are needed for validation.
September 2024 in “Ain Shams Medical Journal” This review discusses the prevalence, pathogenesis, and treatments of androgenic alopecia but reports no new research findings; the authors emphasize the need for further exploration of novel treatment options.
January 2023 in “Annals of dermatology/Annals of Dermatology” This study found that overexpression of miR-1246 in peripheral CD4+ T cells can reduce markers associated with inflammation and T cell activation in severe active alopecia areata, suggesting potential therapeutic benefits.
March 2022 in “Wound practice & research” This review synthesizes current evidence on alopecia areata, detailing its clinical features, pathogenesis, and treatment options, but does not present new clinical results.
April 2021 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in causing alopecia areata.
June 2020 in “Journal of Investigative Dermatology” Hair shaft malformation contributes to Central Centrifugal Cicatricial Alopecia.
September 2019 in “Journal of Investigative Dermatology” This study suggests that in alopecia areata, innate lymphoid cells type 1 may contribute to the disease’s pathogenesis by inducing hair follicle changes similarly to CD8+ T cells.
In this study, researchers observed that dysregulated innate lymphoid cells type 1, alongside CD8+ T cells, may contribute to the pathogenesis of alopecia areata by affecting hair follicle health.
December 2018 in “International journal of women’s dermatology” This study found significant alterations in the scalp and gut microbiome of patients with alopecia areata compared to healthy controls, suggesting a potential link to systemic inflammation and autoimmune response.
May 2017 in “Journal of the American Academy of Dermatology”
466 citations
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August 2004 in “Journal of the American Academy of Dermatology” This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.
82 citations
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May 2010 in “PLoS neglected tropical diseases” This study provides quantitative evidence that secondary syphilis is highly endemic in Cali, Colombia, and many untreated patients have high numbers of circulating Treponema pallidum spirochetes.
46 citations
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January 1988 in “PubMed” This study found that Demodex mites may transport Microsporum canis spores on human skin, suggesting a potential role in microbial movement despite typically being considered harmless.
5 citations
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January 2024 in “American Journal of Translational Research” This research highlighted that the gut microbiota may influence ovarian health, suggesting it could be used as a biomarker for early diagnosis and treatment of diseases like PCOS, ovarian insufficiency, and ovarian cancer due to its impact on hormone levels.
3 citations
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January 2011 in “International journal of trichology” Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.