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A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Hair loss in women may have causes other than hormones.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

The document does not determine if adults with aphallia are fertile.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.