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Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

New treatments for male hypogonadism are effective and should be personalized.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.