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Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Blocking JAK-STAT signaling can lead to hair growth.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.