Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that hair follicle matrix progenitors differentiate into various layers asynchronously, with early progenitors forming the companion layer and later progenitors generating the inner root sheath and hair shaft.

This study found that perifollicular mineralization in old toy poodle bitches was associated with high mineralization levels in other tissues.

This study found that patients with primary cicatricial alopecia are at higher risk of developing various comorbidities, including systemic lupus erythematosus, hypothyroidism, and dermatological conditions, compared to controls.

Complex basal cell carcinomas need personalized treatment due to unique genetic mutations.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

This study identified collagen XXII as a novel extracellular matrix protein specifically present at tissue junctions, where it functions as a cell adhesion ligand for skin epithelial cells and fibroblasts.

Idiopathic hypoparathyroidism is rare and can be managed with dihydrotachysterol.

In this study, sweat duct differentiation was found to be a rare feature in trichilemmal cysts, occurring in only 0.97% of cases, and was likely under recognized.

In this research, the authors identify coordinated mechanical forces as crucial for hair follicle development in mammals, with contractile, proliferative, and proteolytic activities facilitating the formation and sectioning of epithelial structures crucial for forming a functional tissue.

This study in adult mice found that somatosensory axons innervating Merkel cells in the skin are highly plastic, with significant remodeling in response to epithelial turnover, and that Merkel cells play a role in limiting axonal branching and promoting their maturation.

This study explored dermatoscopic and histopathologic findings of central centrifugal cicatricial alopecia beyond the vertex scalp, suggesting that dermatoscopy might serve as a less invasive diagnostic tool for subclinical disease.

This study examined the clinicopathological characteristics of cutaneous squamous cell carcinoma on the scalp and ear but reported no new results on its association with androgenetic alopecia.

This case report describes the first recorded instance of congenital triangular alopecia in the mid-frontal scalp region, challenging the assumption that it is restricted to the frontotemporal area.

This study found that Merkel cell clusters require Frizzled6 signaling for their polarity information, while other hair follicle-associated structures align their orientation based on the hair follicle itself.

This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.

This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

This study found that while niche architecture optimizes organ efficiency during hair follicle growth, it is not essential for the function of stem cell-derived tissues.

This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.

In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.

This study reports that in mice, CaR plays a critical role in sensing the epidermal Ca2+ gradient, influencing keratinocyte differentiation, and affecting epidermal development.

This case report describes a rare instance of melanocytic matricoma, a benign pigmented papule found in sun-damaged skin of an elderly individual, highlighting its distinct clinical and pathological features.

This study found that calretinin immunoreactivity may help identify the innermost cell layer of the outer root sheath in anagen hair follicles and certain cutaneous adnexal proliferations with follicular, sebaceous, and eccrine differentiation.

This study found evidence that polythelia pilosa, previously excluded from classification, should be reintroduced as it marks true aberrant mammary structures in men and hirsute women.

This study found that hair cortisol levels in black-tailed prairie dogs, influenced by factors like predation risk and lactation, were associated with reproductive success, supporting the Cort-Adaptation hypothesis.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This correspondence discusses eyebrow alopecia in the context of centrofacial trichoblastomatosis and reports no new clinical findings.

This study identified a new variety of central centrifugal cicatricial alopecia that includes patchy hair loss on the lateral and posterior scalp in African-American women, which could be misdiagnosed as traction alopecia without dermatoscopy and pathology.

In this study, researchers examined the pancreas of immature Iraqi blackbuck, finding unique histological features, such as underdeveloped goblet cells and similar distribution of Langerhans islets across genders, which could enhance understanding of the species' pancreatic physiology and pathology.

This study reports that caspase-14's expression pattern in the epidermis and hair follicles is highly conserved across diverse mammalian species, suggesting its early evolutionary role in mammalian skin maturation.

This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.