March 2026 in “Frontiers in Medicine” This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.
July 2025 in “Clinical Dermatology Review” In this case report, researchers observed multiple trichofolliculomas in family members, noting this as a rare manifestation of typically singular hair follicle hamartomas.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that targeting both hormonal and immune pathways improved treatment outcomes in androgenetic alopecia patients with an under-recognized inflammatory component called PIILIF, which may contribute to treatment resistance.
39 citations
,
October 1967 in “British Journal of Dermatology” Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
May 2021 in “Pakistan Journal of Medical and Health Sciences” This study found that among Pakistani men with hair loss, the M type pattern was the most prevalent according to BASP classification.
13 citations
,
February 2015 in “Actas Dermo-Sifiliográficas” This review discusses the histologic features of nonscarring alopecia and highlights the importance of clinical-pathological correlation for accurate diagnosis, but reports no new clinical results.
1 citations
,
January 2017 in “대한피부과학회지” This study observed that male pattern hair loss patients are getting diagnosed earlier and presenting with milder forms, possibly due to early puberty, and noted frequent familial predisposition and comorbidities like seborrheic dermatitis.
18 citations
,
January 2013 in “Dermatology Online Journal” This case report describes a 19-year-old woman with typical clinical and histopathological findings of trichofolliculoma, a rare hair follicle hamartoma usually located on the face or scalp.
January 2016 in “Indian dermatology online journal” This case study diagnosed a 60-year-old woman with frontal fibrosing alopecia after histopathological analysis showed characteristic scarring patterns in the hairline area.
December 2021 in “IP Indian journal of clinical and experimental dermatology” In this study, trichoscopy was identified as a useful non-invasive tool to aid in the diagnosis of female pattern hair loss, with peri pilar sign and hair diameter variability being common findings.
179 citations
,
December 2004 in “Journal of The American Academy of Dermatology” This study observed that frontal fibrosing alopecia in postmenopausal women involves selective follicular inflammation, and finasteride treatment may slow disease progression, suggesting a potential androgen-related component.
2 citations
,
December 2023 in “International Journal of Dermatology” In this study, researchers identified a unique variant of alopecia areata characterized by an increase in telogen hair follicles and minimal inflammation present in the microenvironment.
24 citations
,
September 2002 in “Dermatologic Surgery” This study describes the anatomy of arrector pili muscles in scalp hair follicular units, proposing a model where a single muscle structure is shared by all follicles within a unit.
November 2018 in “Skin appendage disorders” The document concludes that a woman has both Frontal Fibrosing Alopecia and Lichen Simplex Chronicus, a previously unreported combination of conditions.
July 2026 in “Editora Pasteur eBooks” This narrative review explores current understanding and management of female pattern hair loss, highlighting the role of genetic and environmental factors, and discussing diagnostic approaches like trichoscopy alongside emerging therapeutic strategies.
4 citations
,
September 2020 in “Journal of Cutaneous Pathology”
4 citations
,
April 2013 in “Actas Dermo-Sifiliográficas” This study found that hairline measurements in white Spanish women differ from those previously reported for American women, which may be important for hair transplantation evaluations in alopecia cases.
March 2026 in “Anais Brasileiros de Dermatologia” Lichen planopilaris and frontal fibrosing alopecia are likely distinct diseases with different tissue involvement.
This chapter reviews the causes, clinical characteristics, and modern management of male and female pattern hair loss but reports no new clinical results.
November 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This perspective highlights evidence suggesting inflammation plays a significant role in male and female pattern hair loss, indicating that targeting inflammatory pathways may improve future therapeutic options.
1 citations
,
May 2013 in “PubMed” This review discusses the classification of female androgenic alopecia using the Ludwig classification and details the hair growth cycle but provides no new clinical results.
2 citations
,
June 2012 in “American Journal of Dermatopathology” This case study describes a rare cutaneous follicular hybrid cyst intimately associated with syringocystadenoma papilliferum, proposing a potential relationship with the infrainfundibulum based on keratin expression.
86 citations
,
August 2000 in “Pigment cell research” This study observed that melanogenesis in human hair follicles is linked to anagen phases, with melanocyte activity and enzyme expression being region-specific to the nascent bulb.
December 2021 in “Journal of pharmaceutical research international” This study found that trichoscopy can effectively differentiate female pattern hair loss from chronic telogen effluvium based on specific features like hair shaft diameter variability and density differences, aiding in targeted treatment planning.
5 citations
,
February 2017 in “Australasian Journal of Dermatology” This report describes three cases of hair loss that appear consistent with cicatricial pattern hair loss, a possible new subtype of scarring alopecia presenting in a female pattern hair loss distribution.
February 2009 in “Journal of The American Academy of Dermatology” This study found that HLA-B*57 and HLA-Cw*06 were associated with increased risk of psoriasis vulgaris, while KIR2DL2 was more prevalent in controls, suggesting a protective effect.
14 citations
,
January 2016 in “International Journal of Trichology” This study observed that many female pattern hair loss patients had concurrent conditions such as telogen effluvium, hypothyroidism, and hypertension, with a significant percentage having low Vitamin D levels.
October 2022 in “Hair Transplantation” This article reviews the terminology and factors associated with female hair loss, particularly distinguishing it from male pattern hair loss, but reports no new clinical results.
2 citations
,
June 2001 in “Medical Electron Microscopy” This study observed that the keratinization pattern of trichilemmal cysts in two Japanese women may originate from the proliferation of the outer root sheath in the follicular isthmus of anagen hairs.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.