Trichofolliculoma: A Rare Variant of Hair Follicle Hamartoma

    January 2013 in “ Dermatology Online Journal
    Hilal Gökalp, Mehmet Ali Gürer, Saadet Alan
    TLDR Trichofolliculoma is a rare skin bump on the face or scalp.
    Trichofolliculoma was described as a rare hair follicle hamartoma, often mistaken for other skin disorders due to its lack of distinctive clinical features. It typically presented as a small papule or nodule, primarily on the face and scalp, with a central pore and sometimes a tuft of vellus hairs. The case of a 19-year-old woman with a scalp nodule exemplified these characteristics, and histological examination confirmed the diagnosis. Although benign, trichofolliculoma could recur after excision, as seen in this case. The condition was believed to result from abortive differentiation of skin cells toward hair follicles, with histopathological features including a dilated central follicle and smaller secondary follicles. Malignant transformation was rare but had been reported.
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