Trichofolliculoma: A Rare Variant of Hair Follicle Hamartoma

Trichofolliculoma, a rare benign tumor of hair follicle origin, was typically non-invasive and only occasionally recurred locally after surgical removal. However, this report from 1979 described a unique case involving a 57-year-old man with a trichofolliculoma on his cheek that exhibited perineural invasion, a feature not previously documented in the 59 recorded cases. The tumor, measuring 1.6 cm, was surgically excised and showed a central keratin-filled cyst with squamous epithelium. The observation of perineural invasion highlighted a potential clinical significance, suggesting that trichofolliculomas might occasionally exhibit more aggressive behavior than previously understood.