Cicatricial Alopecia with Particular Trichoscopic and Histopathological Features
November 2018
in “
Skin appendage disorders
”
cicatricial alopecia trichoscopic histopathological eyebrow loss frontal hairline recession thick skin short broken hairs vellus hairs follicular openings perifollicular scaling broom hair fibers hyperkeratosis acanthosis papillomatosis perifollicular fibrosis lymphoplasmacytic infiltrate Frontal Fibrosing Alopecia Lichen Simplex Chronicus lymphocytic scarring alopecia lichenified patches scarring alopecia hairline recession broken hairs scaling broom hair fibrosis lymphocytic infiltrate FFA LSC
TLDR The document concludes that a woman has both Frontal Fibrosing Alopecia and Lichen Simplex Chronicus, a previously unreported combination of conditions.
The document discusses a case of a 69-year-old woman with a 3-year history of hair and eyebrow loss, severe itching, and constant scratching of the scalp. Physical examination showed eyebrow absence, frontal hairline recession, thick skin in the frontoparietal area, and short broken hairs. Trichoscopic findings included the absence of vellus hairs and follicular openings, perifollicular scaling, and broom hair fibers. Histopathology revealed hyperkeratosis, acanthosis, mild papillomatosis, perifollicular fibrosis, and mild lymphoplasmacytic infiltrate around the isthmus. The diagnosis was an association of Frontal Fibrosing Alopecia (FFA) and Lichen Simplex Chronicus (LSC). FFA is a primary lymphocytic scarring alopecia with progressive frontotemporal hairline recession, while LSC is a skin disease characterized by lichenified patches due to constant scratching. The coexistence of both conditions in the same patient had not been reported before this case. The trichoscopic and histopathological findings supported the diagnosis of both conditions.