June 2023 in “British Journal of Dermatology” In this study, baricitinib showed promising results in improving scalp, eyebrow, and eyelash hair loss in adults with severe and very severe alopecia areata over 52 weeks.
19 citations
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September 2013 in “Psychoneuroendocrinology” Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
May 2026 in “European Cells and Materials” In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.
16 citations
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March 2015 in “Clinical and experimental dermatology” This study found that mycophenolic acid promotes dermal papilla cell proliferation and anagen hair follicle induction in mice, suggesting potential as a treatment for hair-loss disorders.
2 citations
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January 2007 in “edoc (University of Basel)” This study identified Aquilaria sinensis and Piper cubeba as tropical plants with potential anti-androgenic and anti-estrogenic properties that could help prevent or alleviate benign prostatic hyperplasia and prostate cancer.
1 citations
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July 2023 in “Biomimetics” This study found that a hair-coating polyphenol complex significantly enhanced the mechanical strength, UV protection, and antistatic properties of damaged hair, suggesting potential benefits for hair treatment.
6 citations
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June 2011 in “British Journal of Dermatology” This study found that individuals with alopecia areata had significantly higher serum levels of retinol-binding protein 4 and increased IgG immunoreactivity against it, suggesting a role in the disease's pathogenesis.
5 citations
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June 2021 in “Journal of neurology, neurosurgery and psychiatry” This study found that females exposed to high cumulative doses of cyproterone acetate had a 6–20 fold increased risk of developing meningiomas compared to those on lower doses.
2 citations
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November 2023 in “International Journal of Preventive Medicine and Health (IJPMH)” This study explored the effects of a 50% hydroalcoholic UPBF extract on BPH in testosterone propionate-induced rats, finding significant improvements in prostate-related parameters and lower urinary tract symptoms at a 200 mg/kg dose, suggesting potential use in BPH management.
1 citations
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February 2014 in “Archiv Der Pharmazie” This study demonstrated that steroidal carbamates 7–10 altered mRNA expression related to lipid metabolism in hamster flank organs and inhibited 5α-reductase activity without binding to the progesterone receptor.
September 2023 in “Journal of The American Academy of Dermatology” This announcement discusses the recent FDA approval of baricitinib for treating severe alopecia areata in adults and reports no new clinical results.
11 citations
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November 2011 in “Neuroreport” In this study, paroxetine's antihyperalgesic effect in a rat model of neuropathic pain was shown to be mediated by increased levels of the neurosteroid allopregnanolone in the spine.
October 2023 in “Benha Journal of Applied Sciences” This review evaluates the role of the nuclear receptor PPAR- in skin diseases, highlighting its regulation of inflammation, lipid metabolism, and immune response, and suggests that PPAR-agonists could be promising therapies for conditions like psoriasis and atopic dermatitis.
21 citations
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September 2021 in “New Phytologist” This study found that the transcription factor HB24 plays a critical role in root hair elongation in Arabidopsis thaliana by promoting the conversion of indole-3-butyric acid to indole-3-acetic acid through regulation of IBR1 expression.
April 2023 in “Journal of Investigative Dermatology” In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
16 citations
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January 2023 in “Regenerative Biomaterials” This study examined 3D-printed scaffolds coated with polydopamine and observed that they significantly enhanced osteogenesis and angiogenesis in vitro and in a rat cranium defect model, suggesting their potential for repairing large bone defects.
2 citations
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October 1951 in “Journal of gerontology” This study reported on the excretion levels of pantothenic acid in patients experiencing achromotrichia and alopecia but did not present new clinical results.
232 citations
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June 1975 in “Journal of Steroid Biochemistry” In this study, a treatment regimen combining cyproterone acetate and ethinyl estradiol significantly improved acne and seborrhoea in most women after three months, but had varied effects on hirsutism and alopecia.
52 citations
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July 1998 in “Urology” This study found that liarozole is more effective than cyproterone acetate for improving PSA response and survival in metastatic prostate cancer after first-line endocrine therapy, while maintaining quality of life.
8 citations
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August 2018 in “BMJ Case Reports” This case report describes a patient who experienced rapid hair depigmentation after starting pazopanib for metastatic renal cell carcinoma, which may suggest therapy success despite being distressing.
25 citations
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July 2006 in “Journal of Neurochemistry” This study found that chronic exposure to and withdrawal of progesterone influenced the expression and function of GABA A receptors in rat hippocampal neurons through its metabolite 3α,5α‐THPROG.
18 citations
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December 2016 in “European journal of pharmacology” In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.
1 citations
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October 2025 in “Frontiers in Immunology” In this study, researchers analyzed adverse events linked to avacopan using FDA data, finding no high-priority safety concerns but identifying five potential new adverse events, including alopecia, primarily among American patients, and noting a higher risk of liver dysfunction in Japanese patients.
January 2026 in “Dermatologic Therapy” This study found that elevated tissue RBP4 levels correlate with disease severity in alopecia areata and decrease after effective baricitinib treatment, while the rs3758539 polymorphism is linked to disease susceptibility but not to treatment response.
January 2025 in “Regenerative Biomaterials” In this study, a new pH-responsive hydrogel composed of polyvinyl alcohol and boric acid was found to release salvianolic acid B effectively, reducing excessive scar formation and enhancing tissue regeneration during early-stage wound healing.
1 citations
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July 2025 in “Journal of Photochemistry and Photobiology B Biology” Photobiomodulation helps protect hair follicle cells from damage caused by DHT.
47 citations
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March 2019 in “Journal of immunology research” This review discusses the effects of valproic acid on immune cell activation and gene expression, potentially influencing infection outcomes and suggesting its promise for autoimmune and hypersensitivity condition management.
October 1890 in “Science” Pilocarpin can cause hair regrowth and color change in some cases but not in others, and it may have side effects in animals.
June 2020 in “Journal of Investigative Dermatology” This study of photobiomodulation therapy devices for androgenetic alopecia found variable improvements in hair grade across different skin types and devices, suggesting a need for larger, more comprehensive trials.
31 citations
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October 2010 in “Progress in lipid research” This review discusses the role of LPA(3) in embryo implantation and its genetic connection with prostaglandin signaling, but reports no new clinical results.