research Podophyllotoxin-Loaded Solid Lipid Nanoparticles for Epidermal Targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
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research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
research Understanding the Role of Propionibacterium Acnes in Acne Vulgaris: The Critical Importance of Skin Sampling Methodologies
Precise skin sampling is crucial to understand the role of P. acnes in acne.
research Pattern of Tissue Invasion by Propionibacterium Acnes in Acne Vulgaris
The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Foot Shock Stress Prolongs the Telogen Stage of the Spontaneous Hair Cycle in a Non-Depilated Mouse Model
Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
research Enhancement of Percutaneous Absorption of Finasteride by Cosolvents, Cosurfactant, and Surfactants
Transcutol P best increases Finasteride absorption for hair loss treatment.
research Enhanced Effect of Fibroblast Growth Factor-2-Containing Dalteparin/Protamine Nanoparticles on Hair Growth
FGF-2&D/P nanoparticles can help treat hair loss.
research Topical Formulations Containing Finasteride: Determination of Finasteride Penetration into Hair Follicles Using the Differential Stripping Technique
Formulation P-08-016 better targets hair follicles for baldness treatment.
research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine
Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
research Planning for Maximum Coverage in Surgical Hair Restoration
Walter P. Unger suggests using advanced hair transplant techniques for broader coverage, as they provide natural results and use donor tissue efficiently, while also recommending personalized planning due to the unpredictable progression of baldness.
research Recipient Area Hair Direction and Angle in Hair Transplanting
Dr. Walter P. Unger suggests that copying a person's natural hair direction and angle during transplants leads to a more natural and fuller appearance.
research NUDT15, FTO, and RUNX1 Genetic Variants and Thiopurine Intolerance Among Japanese Patients With Inflammatory Bowel Diseases
Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
research The Potential of Menthol in Enhancing Hair Growth-Promoting Effects of Phyllanthus Niruri Ethanol Extract Gel
Menthol boosts the hair growth and thickness effects of P. niruri extract gel.
research Author's Reply
Dr. Walter P. Unger believes lasers could eventually be important in hair transplantation for achieving natural-looking results, despite current limitations.
research Hair Follicle Characteristics and Fiber Production in South American Camelids
South American camelids should be sheared early, fleece type affects fiber quality, and the S/P follicle ratio doesn't distinguish between Bolivian llama genotypes.
research Acne and Sebaceous Gland Function
Effective acne treatments should reduce sebum, bacteria, and inflammation, with isotretinoin being the best for severe cases.
research Acne, the Skin Microbiome, and Antibiotic Treatment
Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research Intralesional Triamcinolone for Flares of Hidradenitis Suppurativa: A Case Series
Intralesional triamcinolone effectively reduces pain and inflammation in hidradenitis suppurativa flares.
research Long-Term Toxicity Studies on Oxidation Hair Dyes
The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Mechanistic Target of Rapamycin (mTOR) Expression Is Increased in Acne Patients' Skin
Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Acne
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research Role of Insulin Resistance and Diet in Acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Drug-Induced Hair Color Changes
Some medications can change hair color, especially chloroquine and cancer treatments.
research WNT10A, Dermatology and Dentistry
Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
research Hair Growth-Promotion Effects of Different Alternating Current Parameter Settings Are Mediated by the Activation of Wnt/β-Catenin and MAPK Pathway
Certain electric currents can promote hair growth by activating specific cell pathways.