research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
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research Polycystic Ovary Syndrome in Salvador, Brazil: A Prevalence Study in Primary Healthcare
About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
research New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature
New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
research Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats
The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
research Hyperandrogenism and Menstrual Imbalance Are the Best Predictors of Metformin Response in PCOS Patients
High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
research Regenerative Medicine in the Treatment of Specific Dermatologic Disorders: A Systematic Review of Randomized Controlled Clinical Trials
Regenerative medicine shows promise for treating skin disorders like hair loss and vitiligo.
research Long-Term Prophylaxis With Androgens in the Management of Hereditary Angioedema in Emerging Countries
Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.
research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
research Inhaled Medicines for Targeting Non-Small Cell Lung Cancer
Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.
research Efficacy and Safety of Proxalutamide in Severe or Critically Ill COVID-19 Patients: Study Protocol for an Exploratory Trial
The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.
research Innovative Method of Alopecia Treatment by Autologous Adipose-Derived SVF
The document concludes that using a person's own fat cells (SVF) can significantly increase hair thickness and density, suggesting it could be a promising treatment for hair loss.
research Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice
The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
research Scalable and High-Throughput Production of an Injectable Platelet-Rich Plasma (PRP)/Cell-Laden Microcarrier/Hydrogel Composite System for Hair Follicle Tissue Engineering
The developed system could effectively treat hair loss and promote hair growth.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Cytoprotective Role of Human Dental Pulp Stem Cell-Conditioned Medium in Chemotherapy-Induced Alopecia
Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
research Thymol-Loaded PLGA Nanoparticles: An Efficient Approach for Acne Treatment
Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.
research Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke
Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
research Traditional Chinese Medicine Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter
MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
research Cell-Free Fat Extract Restores Hair Loss: A Novel Therapeutic Strategy for Androgenetic Alopecia
A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.
research Phenotypic Heterogeneity in Human Genetic Diseases: Ultrasensitivity-Mediated Threshold Effects as a Unifying Molecular Mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research Emerging 3D Bioprinting Applications in Plastic Surgery
3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
research Alpinetin Promotes Hair Regeneration via Activating Hair Follicle Stem Cells
Alpinetin helps grow hair by turning on hair stem cells and is safe for use.
research Knockout of Integrin Beta1 in Induced Pluripotent Stem Cells Accelerates Skin-Wound Healing by Promoting Cell Migration in Extracellular Matrix
Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
research Agaricus Subrufescens Ameliorates Ovarian Dysfunction and Regulates Altered Biochemical Parameters in Rats with Letrozole-Induced Polycystic Ovarian Syndrome
Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.
research Dihydrotestosterone Induces Arterial Stiffening in Female Mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research Combination of Adipose-Derived Stem Cell Conditioned Media and Minoxidil for Hair Regrowth in Male Androgenetic Alopecia: A Randomized, Double-Blind Clinical Trial
Using adipose-derived stem cell media with minoxidil may help regrow hair in men with hair loss.
research A Rare Manifestation of STING-Associated Vasculopathy with Onset in Infancy: A Case Report
Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.