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The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.

The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.

Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

Cinnamon can help manage symptoms of polycystic ovary syndrome, improve menstrual cycles and fertility, and positively affect cholesterol and blood sugar levels, but more research is needed to confirm these effects and find the best dosage.

Minoxidil with Korean red ginseng improves hair density and thickness more than minoxidil alone.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Chemotherapy may cause recurring hair loss due to an autoimmune response.

Cicatricial alopecia involves scarring hair loss and can be treated with various medications.

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

Autoimmune and inflammatory processes are involved in both scarring and non-scarring types of hair loss.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.

PLD is an effective and safer alternative for treating breast cancer.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.