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Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The document suggests that there might be an autoimmune link between polycystic ovary syndrome and Graves' disease.

Oral contraceptives may cause hair loss in women.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.

Finasteride negatively affects fish reproduction and gonadal development.

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.

Sex steroids affect the MafB gene differently in male and female hamsters.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) was first described in 1721, officially diagnosed in the 1990s, and is now known to be partly genetic and linked to insulin resistance, with increased risk of cardiovascular disease and carbohydrate metabolism issues.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.

Proper nutrition can help manage PCOS symptoms and improve overall health.

Conditions affecting sex development show that sexual diversity is a natural part of human variation.

Removing one ovary helped treat a woman's severe PCOS symptoms when medicine didn't work.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.