Clinical Response to Combined Therapy of Cyclosporine and Prednisone

    December 2013 in “ ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings ”
    Robert C. Gensure
    TLDR Combined prednisone and cyclosporine therapy led to excellent hair regrowth and improved well-being.
    A 13-year-old female with severe alopecia areata, multiple autoimmune diseases, and Down syndrome showed poor response to topical treatments but some improvement with glucocorticoid injections. She had 85-90% scalp hair loss and was treated with oral prednisone and cyclosporine. Over 3 months, she experienced excellent hair regrowth and improved well-being. Prednisone was tapered and discontinued. Several months post-treatment, she developed hyperpigmentation consistent with confluent and reticulated papillomatosis, likely unrelated to her previous therapy. The case highlighted the potential effectiveness of combined cyclosporine and prednisone therapy for late-stage alopecia areata.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community mbp alopecia areata or vitamin deficiency

      in Chat 5 months ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 1 year ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

    Similar Research

    5 / 1000+ results