Correlation of Immunological Variables of Interleukin-17 and Heat Shock Protein-70 in Ethnic Women with Polycystic Ovary Syndrome

    September 2024 in “ South Eastern European Journal of Public Health ”
    Zahraa HA. Abdulla, Sahlah KH. Abbass, Evan MO. Mustafa
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    TLDR Treatment improved PCOS symptoms and reduced BMI and certain immune factors.
    This study investigated the therapeutic effects on immunological and clinical variables in 35 ethnic women with polycystic ovary syndrome (PCOS) in Kirkuk, Iraq. Over a period from February to November 2023, patients underwent treatment involving dietary changes, oral contraceptives, fertility drugs, sugar-reducing medications like Metformin, and nutritional supplements. After three months, significant improvements were observed in clinical signs such as ovulation and menstrual disorders, obesity, hirsutism, and acne. Additionally, there was a notable decrease in body mass index (BMI) and immune factors, specifically Heat Shock Protein 70 and Interleukin-17, with a significant positive correlation between these two immunological variables.
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