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The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.

Bioengineered salivary glands in mice can produce saliva when tasting sour or bitter, but have different protein levels and nerve signals compared to natural glands.

Substance P helps hair grow longer and faster.

No single biomarker is reliable enough for diagnosing and assessing SLE.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Hair follicle culture helps develop new treatments for hair loss.

Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.

A new nanoemulsion increases oxygen for hair cells, leading to better hair growth.

Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Thyroid function affects skin health, with a complex interaction between the two.

Early treatment of superficial fungal infections in immunocompromised patients is crucial.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.