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    Glossary Oral Retinoids

    medications derived from vitamin A for severe skin conditions

    Oral retinoids are a class of medications derived from vitamin A, used to treat various skin conditions, including severe acne and psoriasis. They work by regulating cell growth and differentiation, which can help reduce inflammation and promote healthier skin. These medications can have significant side effects, so they are typically prescribed under strict medical supervision.

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      Oral Retinoids: Present Status

      research Oral retinoids-present status

      108 citations , November 1980 in “British Journal of Dermatology”
      This article reviews the current status of oral retinoids in dermatology and reports no new clinical findings.
      Adverse Reactions to Oral Retinoids: An Update

      research Adverse Reactions to Oral Retinoids An Update

      53 citations , October 1993 in “Drug Safety”
      Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
      Oral Retinoids in Dermatology

      research Oral Retinoids in Dermatology

      52 citations , June 1981 in “International Journal of Dermatology”
      Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

      research Monilethrix treated with oral retinoids

      26 citations , May 1991 in “Clinical and experimental dermatology”
      In this study, oral etretinate resulted in increased hair length and loss of beading in a childhood monilethrix case, while the scalp's keratosis pilaris persisted.
      Efficacy of Oral Retinoids in Treatment-Resistant Lichen Planopilaris

      research Efficacy of oral retinoids in treatment-resistant lichen planopilaris

      16 citations , October 2014 in “Journal of the American Academy of Dermatology”
      This study found that oral retinoid therapy may provide clinical improvement in a small percentage of patients with treatment-resistant lichen planopilaris, although it is not commonly used as a first-line treatment.

      research Collodion baby case series: the success of oral retinoic acid

      4 citations , May 2018 in “Türk pediatri arşivi : İstanbul çocuk kliniği dergisi”
      This study reported dramatic improvements in five collodion baby patients with lamellar ichthyosis treated with oral retinoic acid, noting hair loss as the sole adverse effect, emphasizing the treatment's promising efficacy for physicians.

      research Netherton Syndrome – Responding to Oral Retinoids

      May 2025 in “International Journal of Trichology”
      This case report highlights a 7-year-old boy with suspected Netherton syndrome who presented with itchy lesions, hair abnormalities, and elevated immunoglobulin E levels. The authors report complete resolution of symptoms with oral Acitretin after failed methotrexate treatment.
      Acne

      research Acne

      231 citations , April 2005 in “The New England Journal of Medicine”
      This article discusses the treatment considerations for a 17-year-old boy with a six-month history of acne but reports no new research findings.
      Lichen Planus

      research Lichen planus

      155 citations , June 2009 in “International Journal of Dermatology”
      This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
      Management of Primary Cicatricial Alopecias: Options for Treatment

      research Management of primary cicatricial alopecias: options for treatment

      98 citations , May 2008 in “British Journal of Dermatology”
      This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.
      Management of Acne

      research Management of acne

      78 citations , February 2011 in “Canadian Medical Association Journal”
      This introduction highlights the impact of acne vulgaris on quality of life and the complexity of selecting effective treatments, but it presents no new clinical results.
      Effects of Dermatological Medications on Male Fertility

      research Dermatological medication effects on male fertility

      55 citations , July 2013 in “Dermatologic therapy”
      This review explores the impact of various medications on male fertility, highlighting reversible negative effects from methotrexate, finasteride, and ketoconazole, while reporting no adverse fertility effects for oral retinoids and certain immunosuppressants.

      research Treatment of hirsutism and acne in hyperandrogenism

      54 citations , June 2006 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism”
      This review discusses the management of hirsutism and acne in women with polycystic ovary syndrome, highlighting the partial effectiveness of current treatments and suggesting a combined approach of medication and hair removal.
      Medical Therapy for Frontal Fibrosing Alopecia: A Review and Clinical Approach

      research Medical therapy for frontal fibrosing alopecia: A review and clinical approach

      37 citations , April 2019 in “Journal of The American Academy of Dermatology”
      This review assessed the effectiveness of various treatments for frontal fibrosing alopecia and found that intralesional steroids and 5α-reductase inhibitors showed the most positive outcomes in slowing or halting hair loss, though the lack of placebo-controlled studies and consistent outcome measures limits definitive conclusions.
      Frontal Fibrosing Alopecia: Efficacy of Treatment Modalities

      research Frontal fibrosing alopecia: efficacy of treatment modalities

      14 citations , April 2019 in “International Journal of Women's Health”
      This review highlights current treatment options for frontal fibrosing alopecia, noting that 5-α-reductase inhibitors, intralesional steroids, and hydroxychloroquine have the highest evidence of effectiveness, while other therapies show variable results and need further research.
      Hair Diseases: A Big Problem on a Small Surface

      research Hair diseases: a big problem on a small surface

      4 citations , January 2016 in “Postepy Dermatologii I Alergologii”
      This article discusses various hair diseases and emphasizes their significant impact despite affecting a small area, but does not report new clinical findings.