Prognosis and Management of Congenital Hair Shaft Disorders Without Fragility—Part II

    June 2016 in “ Pediatric Dermatology ”
    Gaurav Singh, Mariya Miteva
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    TLDR Some congenital hair disorders improve with age and can be managed with treatments like minoxidil, retinoids, supplements, and gentle hair care, but there's no cure.
    The document, based on 96 articles, reviewed congenital hair shaft disorders without fragility, noting improvements in conditions like pili torti, trichorrhexis invaginata, woolly hair, and pili trianguli et canaliculi during childhood or adulthood. Treatments such as minoxidil were effective for trichorrhexis nodosa and monilethrix, while oral retinoids benefited trichorrhexis invaginata and monilethrix. Biotin and copper supplementation, as well as thyroid hormone, were helpful for pili torti and trichorrhexis nodosa, respectively, and specialized diets were recommended for cases with aminoaciduria. Gentle hair care was the primary management strategy, and genetic counseling was suggested for inherited conditions. However, no specific treatments for these abnormalities were identified, and the prognosis varied, with some conditions improving over time.
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