Collodion Baby to Bathing Suit Ichthyosis: A 6-Year Follow-Up

The document discusses a 6-year follow-up case of a male newborn who initially presented with a collodion membrane covering his body, a condition known as Collodion Baby. Over time, the membrane was replaced by large, brown, plate-like scales, leading to a diagnosis of lamellar ichthyosis. The patient was treated with acitretin, vitamin D supplementation, and iron-folic acid. By 7 months, there was a significant reduction in scaling, improvement in scalp hair growth, and resolution of ocular discharge. However, the patient's serum triglyceride levels increased, leading to the withdrawal of acitretin. Over the years, the patient's condition worsened seasonally, requiring the intermittent use of acitretin. By the age of 4, the patient's lamellar scales were confined to the trunk and forehead, suggesting a transition to bathing suit ichthyosis. The patient's management included multidisciplinary collaboration, maintaining hydration, and the use of emollients and oral retinoids. The document emphasizes the need for regular monitoring and follow-up due to the potential for phenotype changes over time.