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GlossaryLamellar Ichthyosis

rare genetic disorder causing thick, plate-like skin scales

Lamellar Ichthyosis (LI) is a rare genetic skin disorder characterized by the formation of large, dark, plate-like scales over the entire body. It is caused by mutations in genes responsible for skin cell shedding and barrier function, leading to excessively thickened skin and impaired moisture retention. This condition is present from birth and requires lifelong management to alleviate symptoms and prevent complications.

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research Skin, Genetic Defects, and Aging

January 2016 in “SpringerBriefs in bioengineering”

Genetic defects and UV radiation cause skin damage and aging.

research Disorders of Keratinization

November 2014

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

research Collodion Baby to Bathing Suit Ichthyosis: A 6-Year Follow-Up

January 2022 in “Indian dermatology online journal”

A baby with a skin condition improved with treatment but developed a rare form of the condition affecting only his trunk.

research Lamellar Ichthyosis: One Case Report

1 citations , January 2019 in “International Journal of Medical Reviews and Case Reports”

Treatment with moisturizers improved the skin condition of a girl with a rare genetic skin disorder.

research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System

16 citations , April 2000 in “Journal of Investigative Dermatology”

The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.

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community Is Min finally working for me? Routine help needed (Abbey Yung inspired) pls im balding ❤️ (long post & lots of Qs)

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A 23-year-old woman with androgenetic alopecia (AGA) is using minoxidil, rosemary oil, and dermastamping for hair loss, and is concerned about the effectiveness of minoxidil. She follows a detailed hair care routine and takes supplements like inositol, magnesium, saw palmetto, iron, multivitamins, vitamin D, and B12.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.