January 2026 in “The FASEB Journal” This upcoming clinical trial at Shenzhen People's Hospital will explore the safety and efficacy of human umbilical cord mesenchymal stem cell-derived small extracellular vesicles as a treatment for androgenetic alopecia in young men, comparing them to minoxidil. Results are not reported yet.
January 2026 in “Journal of Community Medicine and Health Solutions” In this study, the novel topical agent PP405 showed favorable tolerability and increased hair density by over 20% in men with advanced androgenetic alopecia after eight weeks, suggesting a promising potential treatment pending further trials.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a polyherbal hair serum improved hair density and shaft quality while being safe and cosmetically acceptable.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and tested a polyherbal hair serum containing several plant extracts, demonstrating its stability, safety, and effectiveness in promoting hair growth and improving hair quality, providing support for natural alternatives to synthetic hair care products.
November 2025 in “Turkish Journal of Dermatology” This study found that both follicular unit transplantation (FUT) and follicular unit extraction (FUE) are safe and effective for female pattern hair loss, with FUE offering broader indications and higher patient satisfaction.
October 2025 in “International Journal of Social health” This systematic review reported that among men taking finasteride for benign prostatic hyperplasia, total PSA levels decreased by 30% to 50%, and free PSA by up to 45%, with reductions in prostate volume and PSA density observed as well.
September 2025 in “Editora Pasteur eBooks” Low-dose oral minoxidil is as effective as or better than topical minoxidil for hair growth but may cause mild side effects.
August 2025 in “Archives of Dermatological Research” This systematic review and meta-analysis suggest that oral minoxidil may be a safer and more effective option for children with hair disorders and refractory hypertension, though further large-scale trials are needed.
June 2025 in “Frontiers in Pharmacology” This systematic review and meta-analysis found that oral minoxidil improved hair loss symptoms in many patients, with significant improvement in 35%, but 27% experienced adverse events, highlighting the need for further research to confirm its safety and efficacy.
April 2025 in “Cytotherapy” In this case report, a 38-year-old male with androgenetic alopecia showed increased hair density and reduced follicular miniaturization after receiving UC-MSCs derived secretome injections, suggesting potential effectiveness and safety for hair restoration; further research is needed for broader validation.
March 2025 in “Medical & Clinical Research” This review highlights the potential of stem cell-based therapies to revolutionize hair restoration treatments, emphasizing their ability to regenerate hair follicles and enhance hair growth for conditions like androgenetic alopecia.
March 2025 in “Cosmetics” This study found that combining PRP with topical minoxidil or finasteride significantly improved hair density and thickness, with patient satisfaction highest for multiple treatment combinations and longer durations.
This review discusses platelet-rich plasma therapy for hair loss and reports no new clinical results, highlighting its potential benefits, mechanisms of action, and areas needing further research.
January 2025 in “Editora Acadêmica Periodicojs eBooks” This review found that low-dose oral Minoxidil may be a viable alternative to topical Minoxidil for treating androgenetic alopecia, offering similar efficacy but with better adherence and different side effect profiles; consideration of patient-specific factors is important for treatment choice.
This systematic review reports positive outcomes for platelet-rich plasma in aesthetic dermatology applications like skin rejuvenation, hair restoration, wound healing, and fat grafting, but highlights the need for standardized protocols in future research.
June 2024 in “Journal of Cosmetic Dermatology” This study found that when choosing between hair transplant and scalp micropigmentation for female pattern hair loss, scalp micropigmentation is preferred if hair density is at least 104.6 hairs/cm².
This protocol outlines a study to evaluate whether photobiomodulation, alone or with melatonin, promotes hair regrowth in dogs with Alopecia X, reporting no new results yet.
April 2024 in “Journal of cosmetic dermatology” This article discusses the development of liquid platelet-rich fibrin as a potential improvement over platelet-rich plasma for treating androgenetic alopecia and reports no new clinical results.
March 2024 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that platelet-rich plasma therapy may effectively improve hair density and related parameters in men with androgenetic alopecia, with results differing based on specific platelet counts.
November 2014 in “PharmaTutor” This article reviews the efficacy of Finasteride for treating female androgenic alopecia, highlighting increased hair counts and density but reports no new clinical results.
September 2002 in “Dermatologic Surgery” This article offers guidance for hair transplant surgeons on addressing old or poorly executed transplants, focusing on surgical precision and effective use of limited donor hair to enhance cosmetic outcomes.
April 2023 in “Journal of Investigative Dermatology” This review found that most studies from 2012 to 2022 reported positive effects of Platelet-Rich Plasma on hair growth and density in androgenetic alopecia, but more research is needed to refine protocols and explore combination therapies.
October 2022 in “MedNEXT Journal of Medical and Health Sciences” This review found that platelet-rich plasma was effective in increasing hair follicle cell activity and capillary density in alopecia treatment, with enhanced outcomes when combined with microneedling or minoxidil.
April 2019 in “Journal of Investigative Dermatology” This review examines clinical trials on low-level laser therapy for pattern hair loss but reports no definitive conclusions, highlighting the need for more controlled studies to resolve uncertainties.
January 2016 in “대한피부과학회지” This study found that a 0.5-mm microneedle depth was more effective than 0.3 mm for increasing hair density in AGA patients treated with a topical growth factor cocktail.
June 2025 in “Frontiers in Bioengineering and Biotechnology” In this study, the researchers observed that a recombinant human collagen complex with nicotinamide promoted hair growth in rat models, increased hair follicle stem cell survival, and enhanced key protein expression, suggesting potential benefits for hair health and loss prevention.
January 2024 in “Research Square (Research Square)” This study reports that adjusting the valence states of Mo in Pluronic F127-coated MoO3-x nanozymes enhances their selective H2O2-related catalytic activity, showing promise in acute kidney injury treatment and enabling real-time monitoring of therapy effectiveness through ROS-responsive photoacoustic imaging.
72 citations
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December 2012 in “Expert Opinion on Drug Delivery” This review discusses niosomes' increasing popularity in dermatology for topical drug delivery due to their ability to enhance drug penetration, provide sustained release, and carry various drugs, while reporting no new clinical findings.
43 citations
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July 1984 in “Clinical and Experimental Dermatology” This study found that women with common baldness treated with cyclical antiandrogen therapy for 52 weeks experienced increased hair density and a higher percentage of hairs in the anagen growth phase.
22 citations
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October 2019 in “Dermatologic Surgery” This study found that platelet-rich plasma was effective for hair regrowth in women with androgenic alopecia, though less so than minoxidil, but it was associated with improved quality of life responses.