Major Randomized Clinical Studies of Alopecia Treatment With Platelet-Rich Plasma: A Systematic Review

This review found that platelet-rich plasma was effective in increasing hair follicle cell activity and capillary density in alopecia treatment, with enhanced outcomes when combined with microneedling or minoxidil.

This study presents a case of treatment-resistant alopecia universalis that successfully responded to a combination of tofacitinib and oral minoxidil, highlighting a potential therapeutic approach for challenging cases of alopecia areata.

This review outlines recent research on platelet-rich plasma, alone or combined with other therapies, for managing hair loss disorders, and discusses future prospects without reporting new clinical findings.

This review discusses platelet-rich plasma and microneedling for alopecia areata, reporting promising small-scale findings but no new results, and suggests further trials to determine efficacy and specific disease subtype suitability.

This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.

This study reviewed two blinded randomized controlled trials and one prospective cohort study and found that PRP injections may increase hair density and induce hair regrowth in adults with androgenic alopecia and alopecia areata, with notably higher hair counts reported at specific follow-up intervals.

This review discusses various types of hair loss, including androgenetic alopecia, telogen effluvium, and alopecia areata, and reports no new experimental findings.

This study found that 1% topical minoxidil induced significant hair regrowth in patients with alopecia areata, though it was less effective for those with extensive hair loss such as alopecia totalis and universalis.