August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
PCOS is a complex condition that can lead to serious health issues, but early diagnosis and treatment can reduce these risks.
January 2022 in “Acta Scientific Women's Health” Early diagnosis and treatment of PCOS can prevent complications and improve symptoms.
September 2021 in “Research Square (Research Square)” Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.
Eating healthy, exercising, and certain nutrients like myoinositol and omega-3s can help manage PCOS symptoms.
January 2020 in “International journal of current research and review” Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.
April 2019 in “Endocrinology and Metabolism Clinics of North America” Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.
August 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than Metformin in treating symptoms of PCOS in women.
May 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.
March 2014 in “Fertility and Sterility” The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
August 2013 in “Fertility and Sterility” Hair loss is common in women with PCOS and is linked to symptoms like acne and excess hair but not to worse metabolic health.
August 2013 in “Fertility and Sterility” High levels of fatty acids are linked to increased androgen production and inflammation in women with PCOS, which may affect IVF outcomes.
September 2002 in “Fertility and sterility” Female relatives of PCOS patients have a higher chance of showing PCOS symptoms.
August 2023 in “Frontiers in Endocrinology” Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.
45 citations,
November 2021 in “Fertility and Sterility” The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.
36 citations,
March 1987 in “Pediatrics” Minoxidil use during pregnancy can cause excessive hair growth and multiple birth defects in the baby.
19 citations,
January 2019 in “Ginekologia Polska” The combined Myo-inositol and D-chiro-inositol treatment improved weight, hormone levels, and skin conditions in women with PCOS.
14 citations,
January 2020 in “Frontiers in Endocrinology” OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.
2 citations,
December 2017 in “Theriogenology” Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
150 citations,
May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
26 citations,
August 2008 in “Clinical endocrinology” The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.
21 citations,
November 2019 in “Molecular & Cellular Proteomics” Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.
10 citations,
August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
8 citations,
September 2020 in “Journal of adolescent health” Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.
8 citations,
March 2015 in “Molecular Medicine Reports” Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
6 citations,
September 2021 in “Autophagy” Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
5 citations,
January 2023 in “Fertility and sterility” Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.
5 citations,
March 2022 in “Frontiers in Endocrinology” A model using hormone levels, cycle length, and BMI can help identify PCOS in Chinese women but isn't for screening teens.