Metabolic and Hormonal Effects of a Combined Myo-Inositol and D-Chiro-Inositol Therapy on Patients with Polycystic Ovary Syndrome

    January 2019 in “ Ginekologia Polska ”
    Marcin Januszewski, Tadeusz Issat, Alicja Jakimiuk, Malgorzata Santor-Zaczynska, Artur Jakimiuk
    Image of study
    TLDR The combined Myo-inositol and D-chiro-inositol treatment improved weight, hormone levels, and skin conditions in women with PCOS.
    In a study conducted in 2019, 70 women diagnosed with Polycystic Ovary Syndrome (PCOS) were treated with a combined therapy of Myo-inositol (MI) and D-chiro-inositol (DCI) in a 10:1 ratio for 6 months. The results showed significant reductions in body weight, free testosterone (fT), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and insulin levels. Additionally, there was a significant increase in serum sex hormone-binding globulin (SHBG) concentrations and a decrease in serum glucose levels during a standard oral glucose tolerance test (OGTT) after 6 months of treatment. Skin conditions also improved after only three months of treatment. The study concluded that the combination of MI and DCI in a 10:1 ratio was effective in improving both metabolic and hormonal parameters in patients with PCOS.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 7 results

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Have any of you used myoinositol

      in Research/Science  1 upvotes 2 years ago
      The conversation is about using inositol for hair loss, particularly its potential benefits for men, given its success in women with PCOS. The discussion includes treatments like Minoxidil, finasteride, and RU58841.

      community Female androgenetic alopecia (w/ PCOS) starting treatment

      in Female  2 upvotes 1 month ago
      A female with PCOS and androgenetic alopecia is starting treatment with oral Minoxidil, topical Minoxidil 5% with finasteride, and plans to add mesotherapy. She previously tried anti-androgenic contraceptive pills but couldn't tolerate them and is using Myo Inositol for weight management.

      community Methionine? Glycine?

       6 upvotes 9 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

    Similar Research

    5 / 301 results