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This study found that male patients with androgenetic alopecia had lower serum levels of the antioxidant enzyme paraoxonase 1 compared to healthy controls.

In this study, algal oligosaccharides effectively countered key factors in androgenetic alopecia pathogenesis, improving hair growth indicators in vitro and in mice.

This study found that some synthesized 17-oximino-5-androsten-3β-yl esters demonstrated stronger cytotoxicity and antiandrogenic activity against prostate cancer cells than finasteride.

This review discusses lysophosphatidic acid's role in neuropathic pain and cholestatic itch, highlighting its complex signaling pathways, but reports no new clinical results.

This study found that Ishophloroglucin A from brown seaweed may treat androgenic alopecia by inhibiting 5α-reductase and promoting hair growth-related factors in human dermal papilla cells.

This study reports the development of novel 4-amido-Δ4,6-steroids as potential inhibitors of 5α-reductase, showing promising in vitro results for conditions like acne and benign prostatic cancer.

This trial explores whether spironolactone is more effective than cyclines for treating moderate acne in adult women, providing a potential alternative amidst concerns over antibiotic resistance.

This meta-analysis concluded that compound glycyrrhizin combined with conventional treatments enhanced hair regrowth in alopecia areata patients, though it was associated with some mild adverse effects like oedema.

This study found that certain curcumin analogs derived from natural plant sources exhibit anti-androgen activity by inhibiting steroid 5-alpha reductase, identifying key structural features for their potency and safety in treating androgen-related conditions.

This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.

This study found that taxifolin glycosides isolated from Rhododendron mucronulatum showed promise for developing treatments for male pattern hair loss by inhibiting DHT production and enhancing hair growth-promoting factors.

This study found that Annurca apple polyphenolic extracts reprogram hair follicle metabolism in mice, enhancing mitochondrial activity and keratin production while inhibiting some metabolic pathways.

This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.

In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.

This review highlights the promising therapeutic potential of Bacopa monnieri in treating various health conditions, particularly related to neuropharmacology, but emphasizes the need for further clinical research.

In this study, the NADES extract of mangkokan leaves (Polyscias scutellaria) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with a total flavonoid content measured at 4.944 mgEQ/gSimplisia using the disc diffusion method.

This pilot study suggests that lovastatin may counteract stress-induced MICA expression in hair follicles and enhance MICA shedding, potentially offering a complementary approach for alopecia areata treatment.

This review provides an overview of azelaic acid's dermatological uses, mechanisms, and its potential in skin cancer treatment, but reports no new clinical results.

This study reports that a novel nanolipogel with moderate rigidity (NLG-2.5) enhances transdermal delivery of fucosterol, displaying superior permeability, targeting hair follicles, and promoting hair growth in androgenetic alopecia model mice by inhibiting inflammation and androgen pathways and promoting angiogenesis.

This study found that patients with acne vulgaris had significantly lower serum paraoxonase 1 (PON1) activity compared to healthy controls, suggesting that oxidative stress might play a role in the condition's development.

This paper reviewed studies from 2019 to 2025 on the use of olive oil and other derivatives from the European olive tree for skin, hair, and nail care, noting their roles in wound healing and skin aging while highlighting a favorable safety profile.

This study suggests that Ecklonia cava, particularly its component dioxinodehydroeckol, may promote hair growth by enhancing dermal papilla and outer root sheath cell activity in culture and mice models.

This study found that spironolactone treatment can normalize endothelial function and improve cholesterol levels in non-obese patients with polycystic ovary syndrome.

Lacto-fermentation changes amino acid profiles in bovine colostrum, but results are inconsistent.

This review discusses azelaic acid's mechanisms and uses in dermatology, noting its effectiveness in treating conditions like rosacea, acne, and melasma, but reports no new clinical results.

Mycophenolic acid may help hair grow by activating pathways important for hair growth.

This study found that a sub-fraction of Noni fruit, FEA-3, showed hair growth-promoting effects in a rabbit model of androgenic alopecia, similar to Minoxidil.

In this study, a taurine-based ionic liquid was developed to effectively penetrate the skin barrier and deliver antioxidants to hair follicles, reducing oxidative stress and promoting hair regrowth in an androgenic alopecia animal model.

In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.

This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.