16 citations
,
July 2020 in “Health and Quality of Life Outcomes” This study found that health-related quality of life was significantly lower in women with polycystic ovary syndrome, especially those with the anovulatory phenotype, compared to non-PCOS controls attending a tertiary hospital.
7 citations
,
February 2023 in “Obesity” This study found that women with PCOS were more likely than women without PCOS to have multiple weight-loss attempts and perceive themselves as overweight, regardless of their actual obesity status.
1 citations
,
January 2025 in “ARC Journal of Nursing and Healthcare” This study focused on overweight and obese women with polycystic ovary syndrome who underwent lifestyle modification interventions and found notable improvements in BMI, menstrual cycle regularities, hyper-androgenic symptoms, and fertility outcomes, including a 36.2% pregnancy rate post-intervention.
6 citations
,
July 2023 in “Nature cell biology” In this study, re-activating SOX9 in adult epidermal stem cells led to a fate switch towards hair follicle stem cell identity, with altered chromatin dynamics and oncogenic activation, contributing insights into developmental processes and cancer pathways.
2 citations
,
February 2022 in “Pakistan Armed Forces Medical Journal” This study found that women with PCOS reported significant appearance-related distress and social anxiety, especially in social settings.
October 2010 in “Reproductive Biomedicine Online” This study reported that MALDI-TOF Mass Spectrometry profiling demonstrated nearly 100% sensitivity and specificity in detecting adenomyosis and leiomyoma, revealing potential peptide markers for these conditions.
This pilot study found that Optical Coherence Tomography can non-invasively resolve hair follicle density and hair shaft and follicle diameters in patients at varying stages of hair loss.
68 citations
,
December 2011 in “Journal of Investigative Dermatology” This study reported that a three-dimensional hydrogel culture system supports the growth and maintenance of distinct dermal papilla cell types, crucial for skin reconstitution assays in neonatal mice.
2 citations
,
January 2023 in “Skin Appendage Disorders” This study suggests a potential role for systematic scalp examinations in first-degree relatives of patients with pattern cicatricial alopecia.
39 citations
,
April 2023 in “Science Advances” This study identified that bone marrow-derived CD34+ cells act as fibroblast progenitors to enhance tissue regeneration in ischemic limbs by promoting angiogenesis through interactions with macrophages.
71 citations
,
July 2015 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS have elevated serum androgen levels throughout adulthood, with these levels decreasing and variations increasing as they approach menopause.
215 citations
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January 2011 in “Reproductive Biology and Endocrinology” Among reproductive-aged women in Iran, this study found that the prevalence of PCOS varied significantly depending on the diagnostic criteria used, with estimates ranging from 7.1% to 14.6%.
April 2019 in “Sohag Medical Journal” This study found that androgenetic alopecia was the most common cause of hair loss among patients at Sohag University Hospital's hair clinic.
7 citations
,
September 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that the ovarian stromal area to total ovarian area ratio alone is not a strong predictor of biochemical hyperandrogenism in Thai women with PCOS, but combining it with clinical hyperandrogenism improves prediction.
7 citations
,
February 2022 in “International Journal of Pharmaceutics” In a mouse model of androgenetic alopecia, this study found that a safflower oil body nanoparticle loaded with human fibroblast growth factor 10 significantly improved hair regeneration and reduced associated microinflammation without significant toxicity.
99 citations
,
August 2003 in “Fertility and Sterility” This paper discusses polycystic ovary syndrome with a focus on androgen excess as the primary symptom and notes that insulin resistance may contribute to it in many patients, but provides no new research findings.
March 2024 in “Biochimica et biophysica acta. Molecular basis of disease” This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.
2 citations
,
April 2021 in “Journal of Cosmetic Dermatology” This study found that sulforaphane and its related compounds may promote hair follicle growth in mice, suggesting their potential as treatment agents for androgenic alopecia.
August 2023 in “Journal of The American Academy of Dermatology” Recent studies highlighted in this research suggest that alopecia types in men, traditionally thought to affect only certain scalp areas, can also impact the occipital region, which was previously presumed unaffected.
September 2024 in “Journal of the American Academy of Dermatology” This study found that phenoxyethanol is the most common contact allergen in over-the-counter hair loss products, but its role in the development or exacerbation of frontal fibrosing alopecia remains unclear.
May 2026 in “International Journal of Current Pharmaceutical Review and Research” This article discusses the causes of polycystic ovary syndrome, including environmental pollutants, genetics, and oxidative stress, and explains how these factors contribute to symptoms like irregular menstrual cycles and obesity without reporting new clinical results.
August 2013 in “Acta Ophthalmologica” This study found that medications including benzodiazepines, quetiapine, and certain alpha-blockers, along with hypertension and short axial length, were independently associated with an increased risk of Intraoperative Floppy Iris Syndrome during cataract surgery.
71 citations
,
January 2011 in “Orphanet Journal of Rare Diseases” This article reviews IFAP syndrome, an X-linked genetic disorder characterized by ichthyosis follicularis, alopecia, and photophobia, and reports no new clinical findings.
January 2023 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that combining metformin with myo-inositol improved outcomes for women with Polycystic Ovary Syndrome, resulting in a statistically significant increase in normal ovarian size and higher pregnancy rates compared to treatment with metformin alone.
28 citations
,
April 2013 in “Fertility and Sterility” This study found that Caucasian and Asian women with PCOS in the San Francisco Bay Area had a similar prevalence of androgen excess, including hirsutism, across most measures.
16 citations
,
January 2023 in “Cureus” This article discusses the characteristics and potential consequences of polycystic ovarian syndrome, including its effects on fertility and risk for other health conditions, but it reports no new findings.
December 2014 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” In this study, researchers found that overexpressing SOX2 in colorectal cancer cell lines can cause DNA damage and cell death, while repressing it reduces tumor growth and cell aggressiveness.
179 citations
,
July 2005 in “Human Reproduction Update” This review discusses the genetic basis and familial patterns of polycystic ovary syndrome, noting a strong familial component but inconclusive genetic patterns; it reports no new empirical findings.
August 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” In this study, PCOS was found to be highly prevalent among urban, middle socioeconomic status women aged 21 to 30, with common symptoms including oligomenorrhea, weight gain, infertility, hirsutism, and acne.
April 2023 in “Elsevier eBooks” This review discusses the potential male equivalent of polycystic ovary syndrome, examining early-onset androgenic alopecia as a marker and current research on risks and diagnostic recommendations, but it reports no new results.