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Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Finasteride helps reduce heart issues and improves heart function.

Glioblastoma cells can make androgens, which might help the tumor grow.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

The document is a detailed medical reference on skin and genetic disorders.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Estrogens and progesterone are key in regulating melasma pigmentation.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.