research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
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research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents
Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.
research Finasteride in the Treatment of Androgenetic Alopecia
Finasteride effectively treats male pattern baldness, improving hair growth and density.
research Hormone Replacement Therapy for Women with Premature Ovarian Insufficiency: A Comprehensive Review
The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.
research What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women
Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.
research Irreversible And Severe Alopecia Following Docetaxel Or Paclitaxel Cytotoxic Therapy For Breast Cancer
Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.
research Polycystic Ovary Syndrome: A Review for Dermatologists
Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.
research C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research Use of High-Dose Cyproterone Acetate and Risk of Intracranial Meningioma in Women: Cohort Study
High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
research The Impact of Oxidative Stress on Hair
Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness
Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Association of Surgical Risk With Exogenous Hormone Use in Transgender Patients
Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.
research Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness?
Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Female Pattern Hair Loss: A Review Article
Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.
research Clinical, Ultrasound, and Hormonal Markers of Androgenicity in Acne Vulgaris
Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
research The Role of Oral Contraceptives in the Treatment of Hyperandrogenic Disorders
Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
research Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction
Finasteride helps reduce heart issues and improves heart function.
research A Practical Guide for the Study of Human and Murine Sebaceous Glands In Situ
The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Elevated Free Testosterone Levels in Women With Acne
Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
research A Case Series of 20 Women with Hidradenitis Suppurativa Treated with Spironolactone
Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.
research 46,XY DSD Due to Impaired Androgen Production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome
Hair loss in women may have causes other than hormones.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.