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    Glossary Estradiol

    potent estrogen hormone primarily produced in the ovaries

    Estradiol, also known as 17β-Estradiol or E2, is a potent estrogen hormone primarily produced in the ovaries. It plays a crucial role in regulating the menstrual cycle, reproductive system, and secondary sexual characteristics in females. Additionally, estradiol has significant effects on various tissues, including bone, skin, and hair, influencing growth and maintenance.

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    1. Hormonal Treatment of Transgender Women with Oral Estradiol Transgender health · 2018 · 37 citations
    2. Noncontraceptive benefits of the estradiol valerate/dienogest combined oral contraceptive: a review of the literature International Journal of Women's Health · 2014 · 16 citations
    3. Within-person changes of cortisol, dehydroepiandrosterone, testosterone, estradiol, and progesterone in hair across pregnancy, with comparison to a non-pregnant reference group Comprehensive psychoneuroendocrinology · 2020 · 12 citations
    4. Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population Maturitas · 2024 · 5 citations
    5. Effect of the gonadotrophin releasing hormone analogue, goserelin, and oestradiol replacement on sebum excretion rates and hair size in mildly hirsute women Journal of dermatological treatment · 1991 · 4 citations
    6. The dose‐response of percutaneous oestradiol implants on the skeletons of postmenopausal women International Journal of Gynecology & Obstetrics · 1995
    7. Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol Neuroscience · 2004 · 136 citations
    8. The Effects of Estradiol, Androgens and the Selective Estrogen Modulators: Ospemifene, Raloxifene and Tamoxifen on Explant Cultures of Human Breast Tissue UTUPub (University of Turku) · 2013
    9. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    10. Estrus, ovulation, and serum progesterone, estradiol, and LH concentrations in mares after an increased photoperiod during winter. PubMed · 1977 · 83 citations
    11. 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway 2000 · 71 citations
    12. Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol Steroids · 2012 · 55 citations
    13. Differential Suppression of Testosterone and Estradiol in Hirsute Women With the Superactive Gonadotropin-Releasing Hormone Agonist Leuprolide* The Journal of Clinical Endocrinology & Metabolism · 1988 · 49 citations
    14. Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents ˜The œjournal of sexual medicine · 2017 · 36 citations
    15. Presentation of a meningioma in a transwoman after nine years of cyproterone acetate and estradiol intake: case report and literature review Gynecological Endocrinology · 2017 · 34 citations
    16. Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of Mice Journal of Investigative Dermatology Symposium Proceedings · 1999 · 32 citations
    17. Prevention and treatment of experimental prostate cancer in lobund-wistar rats. I. Effects of estradiol, dihydrotestosterone, and castration 1989 · 31 citations
    18. Estrus, Ovulation, and Serum Progesterone, Estradiol, and LH Concentrations in Mares After an Increased Photoperiod During Winter American Journal of Veterinary Research · 1977 · 25 citations
    19. In vitro effects of testosterone, dihydrotestosterone and estradiol on cell growth of human hair bulb papilla cells and hair root sheath fibroblasts. Acta Dermato Venereologica · 1990 · 22 citations
    20. Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride Skin pharmacology and physiology · 2003 · 21 citations
    21. Weak correlations between serum and cerebrospinal fluid levels of estradiol, progesterone and testosterone in males BMC Neuroscience · 2019 · 19 citations
    22. Studies on the persistence of estradiol benzoate and nortestosterone decanoate in hair of cattle following treatment with growth promoters, determined by ultra-high-performance liquid chromatography–tandem mass spectrometry Journal of Chromatography A · 2009 · 18 citations
    23. 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells 2002 · 18 citations
    24. EFFECT OF ESTRADIOL LOCALLY APPLIED TO ABNORMAL SKIN Archives of Dermatology · 1943 · 14 citations
    25. Estrone Sulfate Source of Estrone and Estradiol Formation in Isolated Human Hair Roots: Identification of a Pathway Linked to Hair Growth Phase and Subject to Site-, Gender-, and Age-Related Modulations The Journal of Clinical Endocrinology & Metabolism · 2014 · 11 citations
    26. Estradiol‐induced alopecia in five dogs after contact with a transdermal gel used for the treatment of postmenopausal symptoms in women Veterinary Dermatology · 2015 · 10 citations
    27. The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer Experimental Cell Research · 2019 · 9 citations
    28. Effects of testosterone, dihydrotestosterone and estradiol on growth of human hair outer root sheath keratinocytes in vitro Archives of Dermatological Research · 1991 · 9 citations
    29. Effect of 150 kHz electromagnetic radiation on the development of polycystic ovaries induced by estradiol Valerate in Sprague Dawley rats Journal of Ovarian Research · 2021 · 6 citations
    30. Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss Journal of Dermatological Science · 2018 · 5 citations